Neuroscience

How retrotransposons control the brain

Around half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in various states of decay like an old fashioned 'pull your own' junkyard where parts ...

Oncology & Cancer

Researchers uncover new target for cancer research

In a new paper released today in Nature, BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, detailed a new target for anti-cancer drug development that is sitting at the ...

Genetics

How stress in the intestine influences chromosome inheritance

Inheriting a normal and intact number of chromosomes in germ cells, egg and sperm, is essential for the preservation of all species. With increasing age, the risk of the egg cell not inheriting the normal set of chromosomes ...

Medical research

Manufacturing spermatogonia stem cells

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend on donors for both of ...

Medical research

How an egg cell's 'operating manual' sets the stage for fertility

Recently published work from Carnegie's Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality. Their findings ...

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Germ cell

Germ cells are progenitors of the gametes. These singled-out cells move through the gut to the developing gonads and undergo mitotic proliferation followed by meiosis and differentiation into either eggs or sperm (mature gametes). Plants do not have a germ line set aside in early development. Instead germ cells can come from somatic cells in the adult floral meristem.

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