Poliovirus vaccine trial shows early promise for recurrent glioblastoma
An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.
Cancer
May 21, 2013 |
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Scientists find mutation driving pediatric brain tumors
A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at ...
Genetics
Apr 30, 2013 |
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New minimally invasive, MRI-guided laser treatment for brain tumor found to be promising in study
The first-in-human study of the NeuroBlate Thermal Therapy System finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma (GBM), a malignant type of brain tumor. The ...
Surgery
Apr 05, 2013 |
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Researchers use a type of stem cells from human adipose tissue to chase migrating cancer cells
In laboratory studies, Johns Hopkins researchers say they have found that stem cells from a patient's own fat may have the potential to deliver new treatments directly into the brain after the surgical removal of a glioblastoma, ...
Cancer
Mar 12, 2013 |
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Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice
(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...
Cancer
Mar 05, 2013 |
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Novel combination therapy shuts down escape route, killing glioblastoma tumor cells
Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell ...
Cancer
Feb 26, 2013 |
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5-ALA fluorescence guides resection of recurrent glioblastoma multiforme
Neurosurgeons from UC San Francisco describe the use of 5-aminolevulinic acid (5-ALA) fluorescence in guiding resection of recurrent glioblastoma multiforme (GBM). Ingestion of 5-ALA by a patient before surgery leads to fluorescence ...
Cancer
Feb 19, 2013 |
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Researchers identify enzyme involved in deadly brain tumors
One of the most common types of brain tumors in adults, glioblastoma multiforme, is one of the most devastating. Even with recent advances in surgery, radiation and chemotherapy, the aggressive and invasive tumors become ...
Cancer
Jan 17, 2013 |
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Smaller radiation fields can spare brain when treating tumors
New research from Wake Forest Baptist Medical Center shows that patients suffering from aggressive brain tumors can be effectively treated with smaller radiation fields to spare the rest of the brain and preserve cognition.
Cancer
Jan 09, 2013 |
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New immune therapy treats brain tumors in mice
Using an artificial protein that stimulates the body's natural immune system to fight cancer, a research team at Duke Medicine has engineered a lethal weapon that kills brain tumors in mice while sparing ...
Immunology
Dec 17, 2012 |
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Study finds new targets for drugs to defeat aggressive brain tumor
University of Pittsburgh Cancer Institute (UPCI) researchers have identified over 125 genetic components in a chemotherapy-resistant, brain tumor-derived cell line, which could offer new hope for drug treatment to destroy ...
Cancer
Dec 14, 2012 |
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Metabolic protein launches sugar feast that nurtures brain tumors
Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which ...
Cancer
Nov 26, 2012 |
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Researchers identify novel metabolic programs driving aggressive brain tumors
Researchers at Moffitt Cancer Center have identified metabolic signatures that may pave the way for personalized therapy in glioma, a type of tumor that starts in the brain.
Cancer
Nov 09, 2012 |
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Metabolic protein wields phosphate group to activate cancer-promoting genes
A metabolic protein that nourishes cancer cells also activates tumor-promoting genes by loosening part of the packaging that entwines DNA to make up chromosomes, a team led by scientists at The University of Texas MD Anderson ...
Cancer
Aug 16, 2012 |
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DNA deletions promote cancer, collateral damage makes it vulnerable
Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vul ...
Cancer
Aug 15, 2012 |
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