Alcohol-associated liver disease (ALD), a complex disorder that occurs in some patients who have engaged in excessive alcohol use, is one of the leading causes of chronic liver disease among veterans and liver transplant ...
Apr 19, 2023
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Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. ...
Jul 5, 2023
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Jason Dyck has long believed in the beneficial properties of resveratrol—a powerful antioxidant produced by some plants to protect against environmental stresses. The professor of pediatrics at the University of Alberta ...
Mar 9, 2017
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As a chronic pro-inflammatory disease, obesity is closely associated with the development of various diseases such as type 2 diabetes, cardiovascular disease and cancers. Obesity is now a major concern for public health.
Dec 29, 2022
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A new study led by Associate Professor Ghada Soliman examines how the mechanistic target of Rapamycin (mTOR) protein regulates nutrient metabolism and glucose homeostasis in humans.
Aug 30, 2022
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A recent study published in the journal PNAS shows that young capillary vessels rejuvenate aged pancreatic islets. The finding challenges prevailing views on the causes of age-dependent impaired glucose balance regulation, ...
Nov 17, 2014
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Type 2 diabetes (T2D) is the most common form of diabetes and is associated with many complications. T2D is preventable through weight control and exercise; however, many individuals are unaware that they are at risk and ...
Sep 16, 2013
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(HealthDay)—Treating mice fed a high-fat diet with telmisartan reverses insulin resistance and glucose intolerance, but only when the peroxisome proliferator-activated receptor-δ (PPAR-δ) gene is present, according to ...
Jan 3, 2013
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Diets that are very high in protein are linked to an increased risk for developing type 2 diabetes, and high protein levels have been correlated to poor insulin regulation. However, few studies have investigated whether decreasing ...
Aug 22, 2016
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In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b ...
Feb 8, 2021
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