Pulmonary hypertension is an umbrella term used for many conditions that all result in elevation of the pulmonary arterial pressure. Of interest, many of these completely different clinical and pathophysiological entities ...
Dec 9, 2015
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Researchers in Japan have shown that several different classes of antidepressants increase early growth responses in astrocytes, star-shaped glial cells, which could help develop new treatments.
Sep 15, 2015
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The term "orphan receptor" is used for receptor proteins on the cell surface whose matching binding partner has not yet been identified. The binding partners, usually growth factors, activate the receptor, thus transmitting ...
Sep 10, 2015
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Scientists know that activation of growth factor receptors like epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.
Aug 17, 2015
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(HealthDay)—Iressa (gefitinib) has been approved by the U.S. Food and Drug Administration to treat patients with metastatic non-small-cell lung cancer (NSCLC) with a specific genetic mutation (epidermal growth factor receptor ...
Jul 14, 2015
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Drugs introduced more than a decade ago that target mutations in a protein known as the epidermal growth factor receptor (EGFR) held the promise of personalized treatments for a common form of non-small cell lung cancer. ...
May 20, 2015
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Parvoviruses are a class of viruses that normally infect rodents; in humans, they do not cause any disease symptoms. However, they are able to infect and kill cancer cells. The details behind this biological selectivity on ...
Mar 11, 2015
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Dartmouth researchers have developed a fluorescence imaging technique that can more accurately identify receptors for targeted cancer therapies without a tissue biopsy. They report on their findings in "Quantitative in vivo ...
Nov 14, 2014
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Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems. In a new study, scientists have found that maltreatment affects the way genes are activated, ...
Jul 24, 2014
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(Medical Xpress)—A team made up of researchers from several institutions in France has found that a decoy protein injected into mice, appears to prevent the development of dwarfism. In their paper published in the journal ...
