Regulatory enzyme overexpression may protect against neurodegeneration in Huntington's disease
Treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington's disease (HD) and other neurodegenerative disorders. In a report receiving advance online ...
Neuroscience
Dec 18, 2011 |
5 / 5 (1) |
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Dantrolene protects neurons from Huntington's disease
Huntington's disease (HD) is characterized by ongoing destruction of specific neurons within the brain. It affects a person's ability to walk, talk, and think - leading to involuntary movement and loss of muscle co-ordination. ...
Neuroscience
Nov 25, 2011 |
4 / 5 (1) |
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New drug seems well-tolerated and merits further investigation in patients with Huntington's disease
A novel drug (pridopidine) that stabilises dopamine signalling in areas of the brain that control movement and coordination, appears well tolerated and warrants further study in patients with Huntington's disease (HD), a ...
Neuroscience
Nov 07, 2011 |
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Melatonin delays onset, reduces deaths in mouse model of Huntington's disease
Melatonin, best known for its role in sleep regulation, delayed the onset of symptoms and reduced mortality in a mouse model of Huntington's disease, say researchers at the University of Pittsburgh School of Medicine and ...
Neuroscience
Oct 11, 2011 |
4.7 / 5 (3) |
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New insight into the cellular defects in Huntington's disease
Huntington disease is a devastating neurogenerative disorder that causes a progressive loss of functional capacity and reduced life span. It is an inherited condition caused by a mutant HTT gene. Although this has been known ...
Medical research
Oct 10, 2011 |
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Study finds transcriptional biomarker for Huntington's disease
Huntington's disease, a devastating genetic disorder that causes degeneration of nerve cells in the brain, affects more than 15,000 Americans, and at least 150,000 are at risk of developing the disease. There is no known ...
Medical research
Oct 03, 2011 |
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A step toward controlling Huntington's disease?
Johns Hopkins researchers have identified a natural mechanism that might one day be used to block the expression of the mutated gene known to cause Huntington’s disease. Their experiments offer not an immediate cure, ...
Genetics
Jun 23, 2011 |
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Researchers announce Huntington's disease breakthrough
(Medical Xpress) -- Medical researchers may have uncovered a novel approach to treat an incurable and ultimately fatal neurodegenerative disease that affects hundreds of thousands of people.
Medical research
Jun 02, 2011 |
4.5 / 5 (6) |
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New SRM helps improve diagnosis of Huntington's Disease
A new Standard Reference Material (SRM) from the National Institute of Standards and Technology will help clinical genetics labs accurately diagnose Huntington's disease, an inherited degenerative brain disorder ...
Other
Apr 13, 2011 |
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Scientists find another clue to the origins of degenerative diseases
For years, researchers in genome stability have observed that several neurodegenerative diseases—including Huntington's disease—are associated with cell-killing proteins that are created during expansion of a CAG/CTG ...
Genetics
Apr 11, 2011 |
5 / 5 (1) |
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New discovery proves cause of weight problems in Huntington's disease
The study, which has been published in the scientific journal Cell Metabolism, shows significant changes in the brain's hormone control centre, the hypothalamus. In a series of experiments on mice, which had the mutated Huntin ...
Medical research
Apr 06, 2011 |
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