A collaborative effort between investigators at Roswell Park Comprehensive Cancer Center and the Center for Molecular Immunology (CIM) in Havana, Cuba, has revealed a new strategy for correcting immune dysfunction in cancer ...
Oct 6, 2022
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Alzheimer's disease (AD) is an incurable, progressive neurodegenerative disease affecting over five million people worldwide, and is the leading cause of dementia in the elderly. Currently, intravenous human immunoglobulin ...
Apr 23, 2012
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A new model for understanding which patients with sepsis, COVID-19 and influenza have immune dysfunction and are more likely to suffer poor outcomes has been developed by researchers at the Wellcome Sanger Institute, the ...
Nov 2, 2022
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Researchers at the University of Georgia report in the Journal of Biological Chemistry that an enzyme known as Tumor Progression Locus 2, or Tpl2, plays a key role in directing and regulating several important components ...
Jun 16, 2014
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You think that your immune system is there to protect you. But what happens when it starts working against you?
Apr 23, 2015
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Neuroinflammation caused by a reactive immune system could be tripping off the neurodegeneration seen in certain dementias, multiple sclerosis, and other deadly diseases of the nervous system. A novel molecular imaging technique ...
Jun 8, 2015
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Septic shock is the most severe outcome associated with pathogen infection in the bloodstream. It is a life-threatening condition invariably leading to multiple organ dysfunctions. Currently, septic shock is one of the most ...
Jun 29, 2012
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Metabolic health (normal blood pressure, blood sugar and cholesterol levels, among other factors) influences the effectiveness of influenza vaccinations. Vaccination is known to be less effective in people with obesity compared ...
Apr 18, 2024
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Depending on the signals received, naïve T cells are able to differentiate into mature T cell populations, which play different roles in the immune system. For example, regulatory T cells (Tregs) are important for tamping ...
Nov 25, 2013
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New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand ...
Dec 1, 2016
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