Immunology

Review discusses metabolic reprogramming of T cells

When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...

Diseases, Conditions, Syndromes

Encephalitis: Expert explains why early treatment is important

Encephalitis is a disease that involves the inflammation or swelling of the brain. It can happen because of infections or immune system problems, and early treatment is important. That's why Sarosh Irani, B.M.B.Ch., a neurologist ...

Genetics

Gene editing precisely repairs immune cells

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus ...

Immunology

Evolution of the human immune system in the post-omicron era

It has been four years since the start of the COVID-19 pandemic. SARS-CoV-2 has yet to be eradicated and new variants are continuously emerging. Despite the extensive immunization programs, breakthrough infections (infection ...

HIV & AIDS

The quest to conquer latent HIV and end the AIDS pandemic

A 36-year-old Brazilian man made headlines around the world in 2020 for being the first person to be putatively cured of human immunodeficiency virus (HIV) using an easily accessible and well-tolerated drug cocktail.

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