Neuroscientists find excessive protein synthesis linked to autistic-like behaviors
Autistic-like behaviors can be partially remedied by normalizing excessive levels of protein synthesis in the brain, a team of researchers has found in a study of laboratory mice. The findings, which appear in the latest ...
Autism spectrum disorders
Dec 23, 2012 |
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Blocking 'scaffold' protein inhibits cancer growth, study finds
(Medical Xpress)—Researchers at the Stanford University School of Medicine have devised an entirely novel way to block biological signaling pathways that, when overactive, lead to many types of cancers. They've done so ...
Cancer
Apr 22, 2013 |
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Discovery helps explain how children develop rare, fatal disease
One of 100,000 children is born with Menkes disease, a genetic disorder that affects the body's ability to properly absorb copper from food and leads to neurodegeneration, seizures, impaired movement, stunted ...
Medical research
Apr 30, 2013 |
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Study finds experimental drug inhibits growth in all stages of common kidney cancer
Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's ...
Cancer
Apr 30, 2013 |
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Scientists turns liver cells directly into neurons with new technique
(Medical Xpress) -- Fully mature liver cells from laboratory mice have been transformed directly into functional neurons by researchers at the Stanford University School of Medicine. The switch was accomplished with the introduction ...
Medical research
Oct 07, 2011 |
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Research: Single antibody shrinks variety of human tumors transplanted into mice
Human tumors transplanted into laboratory mice disappeared or shrank when scientists treated the animals with a single antibody, according to a new study from the Stanford University School of Medicine. The antibody works ...
Cancer
Mar 26, 2012 |
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Accused of complicity in Alzheimer's, amyloid proteins may be getting a bad rap
Amyloids—clumps of misfolded proteins found in the brains of people with Alzheimer's disease and other neurodegenerative disorders—are the quintessential bad boys of neurobiology. They're thought to muck up the seamless ...
Alzheimer's disease & dementia
Apr 03, 2013 |
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Is athleticism linked to brain size? Research on mice shows that exercise-loving mice have larger midbrains
Is athleticism linked to brain size? To find out, researchers at the University of California, Riverside performed laboratory experiments on house mice and found that mice that have been bred for dozens of ...
Medical research
Jan 17, 2013 |
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Neuroscientists find promise in addressing Fragile X afflictions
Neuroscientists at New York University have devised a method that has reduced several afflictions associated with Fragile X syndrome (FXS) in laboratory mice. Their findings, which are reported in the journal Neuron, offer ...
Medical research
Sep 19, 2012 |
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Blocking destruction of defective proteins unexpectedly delays neurodegeneration in mice
One might expect that ridding a brain cell of damaged proteins would be a universally good thing, and that impairing the cell's ability to do this would allow the faulty proteins to accumulate within the cell, possibly to ...
Medical research
Aug 15, 2012 |
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Vaccine research shows vigilance needed against evolution of more-virulent malaria
Malaria parasites evolving in vaccinated laboratory mice become more virulent, according to research at Penn State University. The mice were injected with a critical component of several candidate human malaria ...
Medical research
Jul 31, 2012 |
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Making mice comfy leads to better science, researcher says
Nine out of 10 drugs successfully tested in mice and other animal models ultimately fail to work in people, and one reason may be traced back to a common fact of life for laboratory mice: they're cold, according to a researcher ...
Medical research
Mar 30, 2012 |
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How excess holiday eating disturbs your 'food clock'
(Medical Xpress)—If the sinful excess of holiday eating sends your system into butter-slathered, brandy-soaked overload, you are not alone: People who are jet-lagged, people who work graveyard shifts and ...
Medical research
Dec 24, 2012 |
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Autoimmune disease—retraining white blood cells
Symptoms of an autoimmune disease disappeared after a team of scientists retrained the white blood cells. This method is extremely promising for treating diseases such as type I diabetes and multiple sclerosis.
Immunology
Dec 17, 2012 |
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Gene therapy holds promise for reversing congenital hearing loss
A new gene therapy approach can reverse hearing loss caused by a genetic defect in a mouse model of congenital deafness, according to a preclinical study published by Cell Press in the July 26 issue of the journal Neuron. The fi ...
Neuroscience
Jul 25, 2012 |
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