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Liposome

Liposomes are artificially prepared vesicles made of lipid bilayer. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease. Liposomes can be prepared by disrupting biological membranes, for example by sonication.

Liposomes can be composed of naturally derived phospholipids with mixed lipid chains (like egg phosphatidylethanolamine) or other surfactants. Liposomes should not be confused with micelles and reverse micelles composed of monolayers.

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Study finds plasmin—delivered through a bubble—more effective than tPA in busting clots

A new study from the University of Cincinnati has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots than the standard of care, recombinant tissue plasminogen ...

Cardiology created May 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study could aid development of new drugs to treat gout

Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout. The study, led by Liang Qiao, MD, and his colleagues and collaborators, was published March ...

Immunology created Mar 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Don't trust liposomes in your beauty products

New research shows that liposomes in cremes are not capable of transporting active ingredients into the skin.

Medical research created Feb 19, 2013 | popularity not rated yet | comments 0

pH-sensitive liposomal cisplatin improves peritoneal carcinomatosis treatment without side-effects

Scientists at the Oswaldo Cruz Foundation and Federal University of Minas Gerais, led by Dr. Andréa Teixeira-Carvalho and Dr. Mônica Cristina de Oliveira, have developed and characterized a circulating and pH-sensitive ...

Medical research created Aug 27, 2012 | popularity not rated yet | comments 0

Could engineered fatty particles help prevent AIDS?

Could engineered fatty particles help prevent AIDS? Liposomes block HIV infection in early tests; could be a cost-effective preventive for developing countries

HIV & AIDS created Sep 19, 2011 | popularity 5 / 5 (1) | comments 1 | with audio podcast