News tagged with liposomes
Liposome
Liposomes are artificially prepared vesicles made of lipid bilayer. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease. Liposomes can be prepared by disrupting biological membranes, for example by sonication.
Liposomes can be composed of naturally derived phospholipids with mixed lipid chains (like egg phosphatidylethanolamine) or other surfactants. Liposomes should not be confused with micelles and reverse micelles composed of monolayers.
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Study finds plasmin—delivered through a bubble—more effective than tPA in busting clots
A new study from the University of Cincinnati has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots than the standard of care, recombinant tissue plasminogen ...
Cardiology
May 15, 2013 |
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Study could aid development of new drugs to treat gout
Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout. The study, led by Liang Qiao, MD, and his colleagues and collaborators, was published March ...
Immunology
Mar 19, 2013 |
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Don't trust liposomes in your beauty products
New research shows that liposomes in cremes are not capable of transporting active ingredients into the skin.
Medical research
Feb 19, 2013 |
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pH-sensitive liposomal cisplatin improves peritoneal carcinomatosis treatment without side-effects
Scientists at the Oswaldo Cruz Foundation and Federal University of Minas Gerais, led by Dr. Andréa Teixeira-Carvalho and Dr. Mônica Cristina de Oliveira, have developed and characterized a circulating and pH-sensitive ...
Medical research
Aug 27, 2012 |
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Could engineered fatty particles help prevent AIDS?
Could engineered fatty particles help prevent AIDS? Liposomes block HIV infection in early tests; could be a cost-effective preventive for developing countries
HIV & AIDS
Sep 19, 2011 |
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