News tagged with macrophages

Anti-CD47 antibody may offer new route to successful cancer vaccination

(Medical Xpress)—Scientists at the School of Medicine have shown that their previously identified therapeutic approach to fight cancer via immune cells called macrophages also prompts the disease-fighting killer T cells ...

Cancer created May 21, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Do salamanders hold the solution to regeneration?

Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...

Medical research created May 20, 2013 | popularity 4.9 / 5 (7) | comments 4 | with audio podcast

Resistance to visceral leishmaniasis: New mechanisms involved

Researchers from CNRS, Université Toulouse III - Paul Sabatier and IRD have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection. They have shown that dectin-1 ...

Immunology created May 16, 2013 | popularity not rated yet | comments 0

Scientists develop 'magic bullet' nanomedicine for Acute Lung Injury

Researchers at Queen's University Belfast have devised a 'magic bullet' nanomedicine which could become the first effective treatment for Acute Lung Injury or ALI, a condition affecting 20 per cent of all patients in intensive ...

Medical research created May 15, 2013 | popularity 4 / 5 (1) | comments 0

A new 'on' signal for inflammation

(Medical Xpress)—Inflammation is an important response in the body - it helps you to kill off invaders such bacteria that could cause a harmful infection. But if it's chronic or uncontrolled, inflammation can also cause ...

Inflammatory disorders created May 14, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study reveals how melanoma evades chemotherapy

Nitric oxide (NO), a gas with many biological functions in healthy cells, can also help some cancer cells survive chemotherapy. A new study from MIT reveals one way in which this resistance may arise, and ...

Cancer created Apr 08, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scissor-like enzyme points toward treatment of infectious disease

UT Southwestern Medical Center researchers report that a pathogen annually blamed for an estimated 90 million cases of food-borne illness defeats a host's immune response by using a fat-snipping enzyme to ...

Medical research created Apr 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers reveal that immune system like a turbo-charged hybrid car

(Medical Xpress)—Trinity College Dublin scientists have made a significant breakthrough in understanding the immune system that could lead to new treatments for diseases such as sepsis and Type 2 diabetes. A team led by ...

Immunology created Apr 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Cell reprogramming to cure leukaemia and lymphoma

Researchers from the Centre for Genomic Regulation (CRG) in Barcelona reprogramme lymphoma and leukaemia cells to halt their malignancy. Resulting cells remain benign even when no longer subjected to treatment and reduce ...

Cancer created Apr 03, 2013 | popularity 5 / 5 (4) | comments 0

Cholesterol-lowering eye drops could treat macular degeneration

A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease.

Medical research created Apr 02, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Researcher study the dangerous effects of cocaine on HIV patients

Cocaine, already a damaging drug for those with healthy immune systems, can be lethal for those living with human immunodeficiency virus (HIV). Mudit Tyagi, Ph.D., assistant professor of medicine at the George Washington ...

HIV & AIDS created Mar 21, 2013 | popularity not rated yet | comments 0

White blood cells found to play key role in controlling red blood cell levels

Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages – white blood cells that play a key role in the immune response – also ...

Medical research created Mar 17, 2013 | popularity 4.7 / 5 (3) | comments 1 | with audio podcast

Microglia controls neuron production as brain develops

(Medical Xpress)—In a surprise breakthrough, researchers at the UC Davis MIND Institute and their colleagues have found that microglia remove healthy neural progenitor cells (NPCs) through phagocytosis to control neuron ...

Neuroscience created Feb 27, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists find underlying mechanisms behind chronic inflammation-associated diseases

(Medical Xpress)—Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not ...

Inflammatory disorders created Feb 23, 2013 | popularity 4.8 / 5 (10) | comments 4 | with audio podcast

Vitamin D, omega-3 may help clear amyloid plaques found in Alzheimer's

A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease.

Alzheimer's disease & dementia created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Macrophage

Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. ) are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter. Monocytes and macrophages are phagocytes, acting in both non-specific defense (or innate immunity) as well as to help initiate specific defense mechanisms (or adaptive immunity) of vertebrate animals. Their role is to phagocytose (engulf and then digest) cellular debris and pathogens either as stationary or as mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen. They can be identified by specific expression of a number of proteins including CD14, CD11b, F4/80 (mice)/EMR1 (human), Lysozyme M, MAC-1/MAC-3 and CD68 by flow cytometry or immunohistochemical staining. They move by action of Amoeboid movement.

For more information about Macrophage, read the full article at Wikipedia.
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