Scientists from the Trinity Biomedical Sciences Institute (TBSI) have discovered two new ways to block inflammatory macrophages—front-line cells in our immune system that cause complications in a suite of diseases, including ...
Oct 19, 2021
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Inflammation is part of the process that weakens the heart, leading to heart failure. In response to pressure overload such as hypertension, monocytes (a type of white blood cell) enter the heart and become inflammatory macrophages.
Oct 14, 2021
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A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity. Blocking DHPS, the enzyme that ...
Sep 7, 2021
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Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.
Aug 23, 2021
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Blau syndrome is an extremely rare autoimmune disease estimated to occur in fewer than one in a million people. Patients begin to show symptoms before the age of 4, and the symptoms will progress to cause serious complications ...
Jun 25, 2021
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Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans.
Jun 9, 2021
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It's long been known that people living with HIV experience a loss of white matter in their brains. As opposed to "gray matter," which is composed of the cell bodies of neurons, white matter is made up of a fatty substance ...
Jun 2, 2021
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A study using a mouse model of eccentric contraction has revealed that icing injured muscles delays muscle regeneration. The discovery was made by a research group including Associate Professor ARAKAWA Takamitsu and then ...
May 18, 2021
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The triggers and causes of a severe scarring disease of the lungs—idiopathic pulmonary fibrosis, or IPF—remain unclear.
Mar 18, 2021
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Scars inside the abdomen, known as adhesions, form after inflammation or surgery. They can cause chronic pain and digestive problems, lead to infertility in women, or even have potentially life-threatening consequences such ...
Mar 5, 2021
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