News tagged with mass spectrometry
Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.
Medical research Feb 15, 2013 | 4 / 5 (1) | 0 |
Flinders University researchers have discovered that a protein in the brain may play a role in the development of Parkinson's disease – a common degenerative neurological disorder which affects the control of body movements.
Parkinson's & Movement disorders Feb 15, 2013 | 5 / 5 (2) | 0 |
A natural sense of rhythm: Shifting levels of molecules in the blood provide a snapshot of internal 'body-time'
Anybody who has worked the overnight shift will testify that sometimes the time displayed on the clock is not the same as the one in your head. This disconnect is not merely perception; many physiological ...
Medical research Jan 18, 2013 | 5 / 5 (1) | 0
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of ...
Cancer Jan 16, 2013 | not rated yet | 0
Recent research has shown that there are new cells that develop in the heart, but how these cardiac cells are born and how frequently they are generated remains unclear. In new research from Brigham and Women's Hospital (BWH), ...
Cardiology Dec 05, 2012 | 5 / 5 (1) | 0 |
(Medical Xpress)—A new study in the US and Germany has added to our understanding of the human cytomegalovirus (HCMV) and how it manipulates the cells it infects.
Medical research Nov 23, 2012 | 4.8 / 5 (5) | 1 |
Mass spectrometry helps researchers 'watch' how antibiotics attack tuberculosis bacteria inside cells
Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside ...
Medical research Nov 01, 2012 | not rated yet | 0 |
When it comes to germ-busting power, the eyes have it, according to a discovery by University of California, Berkeley, researchers that could lead to new, inexpensive antimicrobial drugs.
Medical research Sep 24, 2012 | 5 / 5 (1) | 0
A pilot study, published in the October 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed that breath testing could be used to discriminate between benign ...
Cancer Sep 16, 2012 | not rated yet | 0
A new 3-D view of the body's response to infection and the ability to identify proteins involved in the response could point to novel biomarkers and therapeutic agents for infectious diseases.
Medical research Aug 10, 2012 | 5 / 5 (2) | 0 |
(Medical Xpress) -- New ways that viruses manipulate the human immune response have been revealed in a research paper just published in Nature involving TCD scientists. Dr Orla Mulhern and Professor Andrew Bowie, School of Bio ...
Immunology Aug 03, 2012 | 5 / 5 (1) | 0 |
On her laptop computer one recent afternoon, University at Buffalo researcher Charmion Cruickshank calls up a mass spectrometry readout showing the breakdown of chemicals in the urine of a child with autism.
Autism spectrum disorders Jul 05, 2012 | 5 / 5 (1) | 2
Biomarkers which could help to predict resistance to chemotherapy in breast cancer patients have been identified by researchers from the University of Hull, UK.
Cancer Apr 12, 2012 | 5 / 5 (1) | 0
A six-year collaboration between two faculty members of Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine has yielded new insight regarding the regulation of intraocular pressure (IOP) in glaucoma ...
Ophthalmology Apr 05, 2012 | not rated yet | 0
(Medical Xpress) -- An important step towards developing a rapid, inexpensive diagnostic method for autism has been take by Uppsala University, among other universities. Through advanced mass spectrometry the researchers ...
Autism spectrum disorders Mar 23, 2012 | 4.5 / 5 (4) | 0 |
Mass spectrometry (MS) is an analytical technique for the determination of the elemental composition of a sample or molecule. It is also used for elucidating the chemical structures of molecules, such as peptides and other chemical compounds. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measurement of their mass-to-charge ratios. In a typical MS procedure:
MS instruments consist of three modules: an ion source, which can convert gas phase sample molecules into ions (or, in the case of electrospray ionization, move ions that exist in solution into the gas phase); a mass analyzer, which sorts the ions by their masses by applying electromagnetic fields; and a detector, which measures the value of an indicator quantity and thus provides data for calculating the abundances of each ion present. The technique has both qualitative and quantitative uses. These include identifying unknown compounds, determining the isotopic composition of elements in a molecule, and determining the structure of a compound by observing its fragmentation. Other uses include quantifying the amount of a compound in a sample or studying the fundamentals of gas phase ion chemistry (the chemistry of ions and neutrals in a vacuum). MS is now in very common use in analytical laboratories that study physical, chemical, or biological properties of a great variety of compounds.
For more information about Mass spectrometry, read the full article at
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