News tagged with metabolic diseases
Lift weights to lower blood sugar? White muscle helps keep blood glucose levels under control
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.
Medical research
Apr 07, 2013 |
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Team finds mechanism that regulates production of energy-burning brown fat
Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue ...
Medical research
Mar 13, 2013 |
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ENCODE project: Researchers catalogue functional elements of the genome
Most of the DNA alterations that are tied to disease do not alter protein-coding genes, but rather the "switches" that control them. Characterizing these switches is one of many goals of the ENCODE project ...
Genetics
Sep 05, 2012 |
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Neurons derived from cord blood cells may represent new therapeutic option
For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood ...
Medical research
Jul 16, 2012 |
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When you eat matters: Study offers drug-free intervention to prevent obesity, diabetes
It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override ...
Medical research
May 17, 2012 |
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Protective gene in fat cells may lead to therapeutic for Type 2 diabetes
In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes. The results may lead to a ...
Medical research
Apr 01, 2012 |
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Biologists find potential drug that speeds cellular recycling
A University of Michigan cell biologist and his colleagues have identified a potential drug that speeds up trash removal from the cell's recycling center, the lysosome.
Medical research
Mar 13, 2012 |
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Study offers insight to how fructose causes obesity, metabolic syndrome
A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes.
Medical research
Feb 27, 2012 |
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Study finds faulty fat sensor implicated in obesity and liver disease
Defects in a protein that functions as a dietary fat sensor may be a cause of obesity and liver disease, according to a study published in the journal Nature, led by researchers at Imperial College London. The findings highli ...
Medical research
Feb 19, 2012 |
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Whole exome sequencing identifies cause of metabolic disease
Sequencing a patient's entire genome to discover the source of his or her disease is not routine – yet. But geneticists are getting close.
Genetics
Feb 03, 2012 |
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Defective cellular waste removal explains why Gaucher patients often develop Parkinson's disease
Gaucher disease causes debilitating and sometimes fatal neurodegeneration in early childhood. Recent studies have uncovered a link between the mutations responsible for Gaucher disease and an increased risk ...
Parkinson's & Movement disorders
May 23, 2013 |
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Discovery of new hormone opens doors to new type 2 diabetes treatments
Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in ...
Diabetes
May 07, 2013 |
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Type 1 diabetes and heart disease linked by inflammatory protein
Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...
Inflammatory disorders
May 07, 2013 |
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Researchers discover endogenous antibiotic in the brain
Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. ...
Medical research
May 06, 2013 |
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Research suggests link between elevated blood sugar, Alzheimer's risk
(Medical Xpress)—A new University of Arizona study, published in the journal Neurology, suggests a possible link between elevated blood sugar levels and risk for developing Alzheimer's disease.
Alzheimer's disease & dementia
May 06, 2013 |
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Inborn error of metabolism
Inborn errors of metabolism comprise a large class of genetic diseases involving disorders of metabolism. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances (substrates) into others (products). In most of the disorders, problems arise due to accumulation of substances which are toxic or interfere with normal function, or to the effects of reduced ability to synthesize essential compounds. Inborn errors of metabolism are now often referred to as congenital metabolic diseases or inherited metabolic diseases, and these terms are considered synonymous.
The term inborn error of metabolism was coined by a British physician, Archibald Garrod (1857-1936), in the early 20th century (1908). He is known for work that prefigured the "one gene, one enzyme" hypothesis, based on his studies on the nature and inheritance of alkaptonuria. His seminal text, Inborn Errors of Metabolism was published in 1923.
For more information about Inborn error of metabolism, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
