News tagged with metabolic pathways

The metabolic weathervane of cancer

Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from ...

Apr 01, 2013
popularity not rated yet | comments 0 | with audio podcast

Discovery spurred by unique twist of fate

(Medical Xpress)—As people age, or as a result of poor nutrition, heart valves can become damaged by the accumulation of calcium deposits within the tissue. This calcification causes a thickening and hardening ...

Feb 21, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

How cancer cells rewire their metabolism to survive

Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar ...

Jan 31, 2013
popularity 5 / 5 (4) | comments 0

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast