Mitochondria are essential cellular components that act as powerhouses. The fusion of two or more mitochondria, and the fission of a mitochondrion into two units are common phenomena known as "mitochondrial dynamics" and ...
Jan 18, 2023
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About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop ...
Nov 29, 2022
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Sirtuins are a family of anti-aging proteins that help regulate cellular lifespan, metabolism, and resistance to stress. The potential protective effect of these sirtuin enzymes in age-related diseases, including cardiovascular ...
Aug 24, 2021
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Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found ...
Sep 19, 2019
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The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of POMC neurons in the hypothalamus that detect and integrate signals related to the body's energy state and ...
Jun 8, 2017
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Although mitochondria, the tiny capsules that produce energy for the cell, are known to play some role in neurodevelopmental and psychiatric disorders, the contribution of mitochondrial dynamics (mitochondrial trafficking, ...
Jul 19, 2016
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The constant beating of the heart requires an enormous output of energy. To meet this demand, cardiomyocytes are loaded with mitochondria, organelles that generate the majority of energy for cells. These mitochondria are ...
Feb 25, 2016
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Researchers at the University of Miami (UM) have discovered and characterized a previously unknown disease gene linked to the degeneration of optic and peripheral nerve fibers. The study titled "Mutations in SLC25A46, encoding ...
Jul 13, 2015
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(Medical Xpress)—One of the most incredible instruments you might ever get to play with is a fiberoptic imaging wand that you hold against the underside of your tongue. Through a semi-mysterious optical arrangement, the ...
