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The brain on drugs: Defining the neural anatomy and physiology of morphine on dopamine neurons

(Medical Xpress) -- Morphine's analgesic properties are as potent as its addictive potential are problematic. The neural pathway for that addiction is typically associated with dopamine (DA) neurons of the ...

Neuroscience created Oct 04, 2011 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast feature

Morphine and cocaine affect reward sensation differently

(Medical Xpress)—A new study by scientists in the US has found that the opiate morphine and the stimulant cocaine act on the reward centers in the brain in different ways, contradicting previous theories ...

Medical research created Oct 05, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast report

Scientists can now block heroin, morphine addiction; clinical trials possible within 18 months

In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

Neuroscience created Aug 14, 2012 | popularity 4.9 / 5 (30) | comments 8 | with audio podcast

Opiates' side effects rooted in patients' genetics, study shows

Genetics play a significant role in determining which patients will suffer the most from the disturbing side effects of opiates, commonly prescribed painkillers for severe to moderate pain, according to a new Stanford University ...

Medical research created Jun 20, 2012 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

New research finds cause of morphine side effects

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for ...

Medical research created Apr 02, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Reformulated imatinib eliminates morphine tolerance in lab studies

By reformulating the common cancer drug imatinib (Gleevec), researchers have eliminated morphine tolerance in rats – an important step toward improving the effectiveness of chronic pain management in patients, according ...

Medications created Feb 21, 2012 | popularity 4.8 / 5 (5) | comments 3 | with audio podcast

Even small doses of opioids increase risk of road crashes, research finds

Drivers who have taken even a small dose of opioid painkillers have an increased risk of being injured in a car accident, a new study has found.

Medications created Jan 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

Post-operative intravenous acetaminophen may help reduce use of morphine in infants

Among infants undergoing major surgery, postoperative use of intermittent intravenous paracetamol (acetaminophen) for the management of pain resulted in a lower cumulative morphine dose over 48 hours, according to a study ...

Surgery created Jan 08, 2013 | popularity not rated yet | comments 0 | with audio podcast

The pain puzzle: Uncovering how morphine increases pain in some people

For individuals with agonizing pain, it is a cruel blow when the gold-standard medication actually causes more pain. Adults and children whose pain gets worse when treated with morphine may be closer to a solution, based ...

Neuroscience created Jan 06, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Itchy wool sweaters explained: Scientists uncover itch-specific nerve cells in skin

Johns Hopkins researchers have uncovered strong evidence that mice have a specific set of nerve cells that signal itch but not pain, a finding that may settle a decades-long debate about these sensations, ...

Neuroscience created Jan 02, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mamba venom holds promise for pain relief

Scientists have used the venom of Africa's lethal black mamba to produce a surprising outcome in mice which they hope to replicate in humans—effective pain relief without toxic side effects.

Medical research created Oct 03, 2012 | popularity 5 / 5 (5) | comments 0

How a protein meal tells your brain you are full

Feeling full involves more than just the uncomfortable sensation that your waistband is getting tight. Investigators reporting online on July 5th in the Cell Press journal Cell have now mapped out the signal ...

Medical research created Jul 05, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

A new drug to manage resistant chronic pain

Neuropathic pain, caused by nerve or tissue damage, is the culprit behind many cases of chronic pain. It can be the result of an accident or caused by a variety of medical conditions and diseases such as tumors, lupus, and ...

Neuroscience created Apr 30, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

A mother's touch may protect against drug cravings later

An attentive, nurturing mother may be able to help her children better resist the temptations of drug use later in life, according to a study in rats conducted by Duke University and the University of Adelaide in Australia.

Neuroscience created Dec 06, 2011 | popularity 3 / 5 (4) | comments 0 | with audio podcast

Jump in drug-dependent babies worries US hospitals

He's less than two weeks old, but he has the telltale signs of a baby in pain: a sore on his chin where he's rubbed the skin raw, along with a scratch on his cheek. He suffers from so many tremors that nurses ...

Addiction created May 13, 2013 | popularity 5 / 5 (1) | comments 0

Morphine

Morphine (INN) (pronounced /ˈmɔrfiːn/) (MS Contin, MSIR, Avinza, Kadian, Oramorph, Roxanol) is a highly potent opiate analgesic psychoactive drug, is the principal active ingredient in Papaver somniferum (opium poppy, or simply opium), is considered to be the prototypical opioid. Like other opioids, e.g. oxycodone (OxyContin, Percocet, Percodan), hydromorphone (Dilaudid, Palladone), and diacetylmorphine (Heroin), morphine acts directly on the central nervous system (CNS) to relieve pain. Morphine has a high potential for addiction; tolerance and both physical and psychological dependence develop rapidly.

For more information about Morphine, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: pain