(Medical Xpress) -- Morphine's analgesic properties are as potent as its addictive potential are problematic. The neural pathway for that addiction is typically associated with dopamine (DA) neurons of the ventral tegmental ...
(Medical Xpress)—A new study by scientists in the US has found that the opiate morphine and the stimulant cocaine act on the reward centers in the brain in different ways, contradicting previous theories that these types ...
In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.
Aug 14, 2012
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Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems—prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, ...
Apr 9, 2024
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New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy—even if not used during pregnancy itself—could result in a higher likelihood that a mother's ...
Feb 28, 2022
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For years, many pregnant women and surgery patients have suffered from chronic itching when they get spinal or epidural morphine to reduce pain. Now, researchers at the University of Pittsburgh School of Medicine have shown ...
Feb 3, 2021
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Two discoveries—one in the brains of people with heroin addiction and the other in the brains of sleepy mice—shed light on chemical messengers in the brain that regulate sleep and addiction, UCLA researchers say.
Jun 27, 2018
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A new study from Indiana University suggests that a drug proven safe for use in people may prevent opioid tolerance and physical dependence when used in combination with opioid-based pain medications.
Feb 27, 2018
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Researchers have identified a brain mechanism that could be a drug target to help prevent tolerance and addiction to opioid pain medication, such as morphine, according to a study by Georgia State University and Emory University.
Aug 22, 2016
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(Medical Xpress)—Researchers at the School of Medicine have identified a subset of nerve cells that mediates a form of chronic, touch-evoked pain called tactile allodynia, a condition that is resistant to conventional pain ...
Mar 10, 2014
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Morphine (INN) (pronounced /ˈmɔrfiːn/) (MS Contin, MSIR, Avinza, Kadian, Oramorph, Roxanol) is a highly potent opiate analgesic psychoactive drug, is the principal active ingredient in Papaver somniferum (opium poppy, or simply opium), is considered to be the prototypical opioid. Like other opioids, e.g. oxycodone (OxyContin, Percocet, Percodan), hydromorphone (Dilaudid, Palladone), and diacetylmorphine (Heroin), morphine acts directly on the central nervous system (CNS) to relieve pain. Morphine has a high potential for addiction; tolerance and both physical and psychological dependence develop rapidly.
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