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News tagged with oncogene

New compound discovered that rapidly kills liver cancer

Scientists have identified a new compound that rapidly kills hepatocellular carcinoma (HCC) cells, the most common form of liver cancer and fifth most common cancer worldwide, while sparing healthy tissue. The compound, Factor ...

Cancer created Mar 14, 2012 | popularity 5 / 5 (20) | comments 0 | with audio podcast

Solving puzzle of B-cell lymphoma development

Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce ...

Immunology created Sep 23, 2012 | popularity 4.9 / 5 (7) | comments 0 | with audio podcast

Genetic master controls expose cancers' Achilles' heel

In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...

Cancer created Apr 11, 2013 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Cancer cells and stem cells share same origin: study

Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells. Scientists at the Keck School of Medicine of the University of Southern California (USC) have proven that those ...

Cancer created Jul 18, 2011 | popularity 5 / 5 (4) | comments 1 | with audio podcast

DNA-repairing protein may be key to preventing recurrence of some cancers

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...

Cancer created Jan 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Researchers discover a new therapy that prevents lung cancer growth in mice

Lung cancer is one of the most aggressive types of cancer and the most common cause of death from this disease worldwide. Despite the progress in the molecular biology of lung cancer achieved in recent years, the mechanisms ...

Cancer created Aug 13, 2012 | popularity 5 / 5 (3) | comments 0

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases

A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study published January 31 in the Open Access journal PLOS Pa ...

Cancer created Jan 31, 2013 | popularity 5 / 5 (3) | comments 1

Bioelectric signals can be used to detect early cancer

Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...

Medical research created Feb 01, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Gene deletion drives more than a quarter of breast cancers

A new study shows that the lack of a certain gene occurs in almost 28 percent of human breast cancers, playing a role in some 60,000 breast cancer cases in the United States and 383,000 worldwide this year.

Genetics created Aug 15, 2012 | popularity 4 / 5 (3) | comments 1 | with audio podcast

Why cancer cells change their appearance?

Like snakes, tumour cells shed their skin. Cancer is not a static disease but during its development the disease accumulates changes to evade natural defences adapting to new environmental circumstances, protecting against ...

Cancer created Sep 02, 2011 | popularity 5 / 5 (2) | comments 0

Unlocking the genetic and molecular mystery of soft-tissue sarcoma

Scientists at Joslin Diabetes Center in Boston have uncovered important molecular and genetic keys to the development of soft-tissue sarcomas in skeletal muscle, giving researchers and clinicians additional targets to stop ...

Cancer created Nov 30, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Breaking oncogene's hold on cancer cell provides new treatment direction

Just as people's bodies and minds can become addicted to substances such as drugs, caffeine, alcohol, their cancers can become addicted to certain genes that insure their continued growth and dominance.

Cancer created Dec 08, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Outwitting a brainy gene

(Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller ...

Cancer created May 01, 2012 | popularity 5 / 5 (2) | comments 0

Potential treatment target identified in an animal model of pancreatic cancer

Detailed analysis of genes expressed in circulating tumor cells (CTCs) -- cells that break off from solid tumors and travel through the bloodstream -- has identified a potential treatment target in metastatic pancreatic cancer. ...

Cancer created Jul 01, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New study finds brain tumors can arise from neurons

(Medical Xpress)—Researchers from the US and Japan have shown that an aggressive type of brain tumor can arise from normal cells in the central nervous system such as neurons. The cells revert to an earlier, ...

Cancer created Oct 19, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast report

Oncogene

An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell.

Many cells normally undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target those DNA sequences and their products.

For more information about Oncogene, read the full article at Wikipedia.
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