About half of all tumors are missing a gene called p53, which helps healthy cells prevent genetic mutations. Many of these tumors develop resistance to chemotherapy drugs that kill cells by damaging their DNA.
Oct 22, 2015
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Search for a description of "p53" and it becomes clear that this human protein is widely known for its cancer-fighting benefits, leading to its renown as "the guardian of the genome."
Jan 31, 2019
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A new discovery opens the possibility of developing a novel way to fight ovarian cancer. Researchers at Baylor College of Medicine and the University of Texas MD Anderson Cancer Center have revealed a previously unknown cellular ...
Mar 28, 2018
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Today in Nature Communications, scientists at the Institute for Research in Biomedicine (IRB Barcelona) provide molecular details about Seckel Syndrome, a rare disease that causes microcephaly, or small brain, and growth ...
Jul 7, 2015
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Melbourne scientists have discovered how tumour development is driven by mutations in the most important gene in preventing cancer, p53.
Nov 7, 2018
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Researchers at the Federal University of Rio de Janeiro (UFRJ) and the State University of Rio de Janeiro (UERJ) have made a discovery that could lead to the development of a treatment against more than half of breast cancer ...
Jun 27, 2018
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Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells to stop dividing or even to commit suicide when ...
Jun 30, 2011
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(Medical Xpress) -- Mutations to a gene called p53 have been linked to half of all cancers, leading to tumor growth and the spread of cancerous cells. Now, a Cornell-led study identifies for the first time the mechanisms ...
Aug 24, 2011
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In a new study in mice, researchers have identified a key protein involved in the irregular brain cell activity seen in autism spectrum disorders and epilepsy. The protein, p53, is well-known in cancer biology as a tumor ...
Jul 17, 2018
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Researchers at the Stanford University School of Medicine have untangled two distinct ways in which a common, naturally occurring "tumor-suppressor" protein works. The separation of these two functions — which can have ...
May 12, 2011
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