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Genome sequencing provides unprecedented insight into causes of pneumococcal disease

A new study led by researchers from Harvard School of Public Health (HSPH) and the Wellcome Trust Sanger Institute in the UK has, for the first time, used genome sequencing technology to track the changes in a bacterial population ...

Genetics created May 05, 2013 | popularity not rated yet | comments 1 | with audio podcast

Key pathway to stop dangerous, out-of-control inflammation discovered

A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues.

Inflammatory disorders created Apr 09, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Team discovers how cells distinguish friend from foe

(Medical Xpress)—Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give themselves away by ...

Immunology created Apr 01, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Immune systems of healthy adults 'remember' germs to which they've never been exposed

It's established dogma that the immune system develops a "memory" of a microbial pathogen, with a correspondingly enhanced readiness to combat that microbe, only upon exposure to it—or to its components though a vaccine. ...

Immunology created Feb 07, 2013 | popularity 5 / 5 (13) | comments 0 | with audio podcast

Brain displays an intrinsic mechanism for fighting infection

(Medical Xpress)—White blood cells have long reigned as the heroes of the immune system. When an infection strikes, the cells, produced in bone marrow, race through the blood to fight off the pathogen. ...

Medical research created Nov 19, 2012 | popularity 5 / 5 (3) | comments 2 | with audio podcast

Hepatitis C treatment's side effects can now be studied in the lab

(Medical Xpress)—The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg ...

Diseases, Conditions, Syndromes created Nov 16, 2012 | popularity 4.5 / 5 (6) | comments 0 | with audio podcast

New DNA vaccine technology poised to deliver safe and cost-effective disease protection

New and increasingly sophisticated vaccines are taking aim at a broad range of disease-causing pathogens, targeting them with greater effectiveness at lower cost and with improved measures to ensure safety.

Medical research created Nov 05, 2012 | popularity 4.8 / 5 (4) | comments 5 | with audio podcast

Blocking key protein could halt age-related decline in immune system

The older we get, the weaker our immune systems tend to become, leaving us vulnerable to infectious diseases and cancer and eroding our ability to benefit from vaccination. Now Stanford University School of Medicine scientists ...

Medical research created Sep 30, 2012 | popularity 5 / 5 (15) | comments 1 | with audio podcast

New invasive non-Typhoidal Salmonella epidemic identified in sub-Saharan Africa

(Medical Xpress)—A new study out today reveals that the emergence and spread of a rapidly evolving invasive intestinal disease, that has a significant mortality rate (up to 45%) in infected people in sub-Saharan ...

Genetics created Sep 30, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Researchers find powerful swine flu strain in Korea

(HealthDay)—A new report shows that a deadly swine flu virus can infect ferrets, highlighting the importance of continuous surveillance of emerging flu strains.

Diseases, Conditions, Syndromes created Sep 10, 2012 | popularity 5 / 5 (2) | comments 0

Researchers reveal crucial immune fighter role of the STING protein

Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.

Medical research created Jun 18, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Discovery helps mice beat urinary tract infections

Scientists at Washington University School of Medicine in St. Louis have found new clues to why some urinary tract infections recur persistently after multiple rounds of treatment.

Medical research created Jun 18, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Scientists find new mechanism by which cell signaling pathway contributes to rheumatoid arthritis development

A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence ...

Immunology created May 20, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Engineered stem cells seek out, kill HIV in living organisms

(Medical Xpress) -- Expanding on previous research providing proof-of-principal that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers have now demonstrated ...

HIV & AIDS created Apr 12, 2012 | popularity 4.8 / 5 (64) | comments 0 | with audio podcast

Scientists boost potency, reduce side effects of IL-2 protein used to treat cancer

The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist ...

Medical research created Mar 18, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Pathogen

A pathogen (from Greek πάθος path "suffering, passion", and γἰγνομαι (γεν-) gignomai (gen-) "I give birth to"), infectious agent, or (more commonly) germ, is a biological agent that causes disease or illness to its host. There are several substrates and pathways whereby pathogens can invade a host; the principal pathways have different episodic time frames, but soil contamination has the longest or most persistent potential for harboring a pathogen.

The body contains many natural defenses against some of the common pathogens (such as Pneumocystis) in the form of the human immune system and by some "helpful" bacteria present in the human body's normal flora. However, if the immune system or "good" bacteria is damaged in any way (such as by chemotherapy, human immunodeficiency virus (HIV), or antibiotics being taken to kill other pathogens), pathogenic bacteria that were being held at bay can proliferate and cause harm to the host. Such cases are called opportunistic infection.

Some pathogens (such as the bacterium Yersinia pestis, which may have caused the Black Plague, the Variola virus, and the Maleria protozoa) have been responsible for massive numbers of casualties and have had numerous effects on afflicted groups. Of particular note in modern times is HIV, which is known to have infected several million humans globally, along with the Influenza virus. Today, while many medical advances have been made to safeguard against infection by pathogens, through the use of vaccination, antibiotics, and fungicide, pathogens continue to threaten human life. Social advances such as food safety, hygiene, and water treatment have reduced the threat from some pathogens.

Not all pathogens are negative. In entomology, pathogens are one of the "Three P's" (predators, pathogens, and parasitoids) that serve as natural or introduced biological controls to suppress arthropod pest populations.

For more information about Pathogen, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.