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News tagged with pathway

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Protein central to cancer stem cell formation provides new potential target

Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.

Cancer created Feb 13, 2013 | popularity 5 / 5 (1) | comments 0

Some autism behaviors linked to altered gene

Scientists at Washington University School of Medicine in St. Louis have identified a genetic mutation that may underlie common behaviors seen in some people with autism, such as difficulty communicating ...

Neuroscience created Feb 12, 2013 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Molecular master switch for pancreatic cancer identified, potential predictor of treatment outcome

A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation

Cancer created Feb 12, 2013 | popularity not rated yet | comments 0

Researchers find possible genetic clues to organ development, birth defects (w/ Video)

(Medical Xpress)—Using cutting-edge time-lapse photography, University of Southern California (USC) researchers have discovered clues to the development of the head at the cellular level, which could point scientists to ...

Medical research created Feb 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Tumor blood vessels prevent the spread of cancer cells

A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University in Sweden in a study published in the ...

Cancer created Feb 11, 2013 | popularity not rated yet | comments 0

New insight into RASopathy-associated lymphatic defects

The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.

Diseases, Conditions, Syndromes created Feb 08, 2013 | popularity not rated yet | comments 0

One hospital night OK for robotic partial nephrectomy

(HealthDay)—Regardless of surgical complexity, most patients undergoing robotic partial nephrectomy (RPN) can be discharged in one day, according to a study published in the February issue of Urology.

Surgery created Feb 07, 2013 | popularity not rated yet | comments 0

Experimental drug combination selectively destroys lymphoma cells

Laboratory experiments conducted by scientists at Virginia Commonwealth University Massey Cancer Center suggest that a novel combination of the drugs ibrutinib and bortezomib could potentially be an effective ...

Cancer created Feb 06, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Brain circuit that makes it hard for obese people to lose weight

(Medical Xpress)—Imagine you are driving a car, and the harder you press on the accelerator, the harder an invisible foot presses on the brake. That's what happens when obese people diet – the less food they eat, the ...

Medical research created Feb 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

MicroRNA molecule may serve as biomarker, target for brain metastases in breast cancer patients

Researchers have identified two molecules that could potentially serve as biomarkers in predicting brain metastases in patients with breast cancer, according to data published in Cancer Research, a publication of the Americ ...

Cancer created Feb 05, 2013 | popularity not rated yet | comments 0 | with audio podcast

Vitamin D, omega-3 may help clear amyloid plaques found in Alzheimer's

A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease.

Alzheimer's disease & dementia created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers use new molecular inhibitors to successfully hit difficult cancer target

Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.

Cancer created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Autism speaks through gene expression

Autism spectrum disorders affect nearly 1 in 88 children, with symptoms ranging from mild personality traits to severe intellectual disability and seizures. Understanding the altered genetic pathways is critical for diagnosis ...

Genetics created Feb 01, 2013 | popularity 3 / 5 (2) | comments 0 | with audio podcast

Blood vessel cells coax colorectal cancer cells into more dangerous state

Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and ...

Cancer created Feb 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

How cancer cells rewire their metabolism to survive

Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar ...

Cancer created Jan 31, 2013 | popularity 5 / 5 (4) | comments 0