How cancer cells rewire their metabolism to survive
Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar ...
Cancer
Jan 31, 2013 |
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How the tilt of a cell-surface receptor prevents cancer
Clear communication between cells is essential to every aspect of the body's internal function. But since cells can't talk, or send emails, how do they communicate?
Cancer
Jan 31, 2013 |
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Researchers generate mutant mouse model useful in treatment of neuromuscular diseases
Researchers at the University of Granada have produced for the first time in the world mice lacking the coenzyme Q10, a rare mitochondrial disease prevailingly affecting children. The researchers needed three ...
Genetics
Jan 29, 2013 |
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Researchers identify possible drug target in breast cancer metastasis
The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries ...
Cancer
Jan 27, 2013 |
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Immune cell suicide alarm helps destroy escaping bacteria
Cells in the immune system called macrophages normally engulf and kill intruding bacteria, holding them inside a membrane-bound bag called a vacuole, where they kill and digest them.
Immunology
Jan 24, 2013 |
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Right target, but missing the bulls-eye for Alzheimer's
(Medical Xpress)—Alzheimer's disease is the most common cause of late-life dementia. The disorder is thought to be caused by a protein known as amyloid-beta, or Abeta, which clumps together in the brain, forming plaques ...
Alzheimer's disease & dementia
Jan 24, 2013 |
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First special edition updating progress on efforts to map human proteins
Almost 10 years after completion of the Human Genome Project in 2003, scientists are making progress toward the next major goal in applying the genetic information in that "Book of Life" in medicine, leaders of an international ...
Genetics
Jan 23, 2013 |
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Scientists find protein that reins in runaway network
Marked for death with molecular tags that act like a homing signal for a cell's protein-destroying machinery, a pivotal enzyme is rescued by another molecule that sweeps the telltale targets off in the nick of time.
Medical research
Jan 22, 2013 |
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Binge drinking can dramatically amplify damage to the liver
Alcoholic liver disease (ALD) is characterized by a fatty liver, hepatitis, fibrosis, and cirrhosis. Binge drinking is on the rise worldwide, and is particularly common in the U.S. A review of studies addressing the effects ...
Addiction
Jan 22, 2013 |
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Ruling the airways: Notch controls bronchial cell fates and distributions
Nestled deep within the body, the epithelial lining of the respiratory system is nonetheless seriously exposed. Its direct contact with environmental air necessitates protective mechanisms that both seal ...
Medical research
Jan 22, 2013 |
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Evidence mounts for role of mutated genes in development of schizophrenia
Johns Hopkins researchers have identified a rare gene mutation in a single family with a high rate of schizophrenia, adding to evidence that abnormal genes play a role in the development of the disease.
Genetics
Jan 22, 2013 |
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Lack of key enzyme in the metabolism of folic acid leads to birth defects
Researchers at The University of Texas at Austin have discovered that the lack of a critical enzyme in the folic acid metabolic pathway leads to neural tube birth defects in developing embryos.
Medical research
Jan 17, 2013 |
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Trapping malaria parasites inside host cell basis for new drugs
One of the most insidious ways that parasitic diseases such as malaria and toxoplasmosis wreak their havoc is by hijacking their host's natural cellular processes, turning self against self. Researchers from ...
Medical research
Jan 16, 2013 |
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Scientists identify natural compounds that enhance humans' perception of sweetness
(Medical Xpress)—University of Florida taste scientist Linda Bartoshuk and her colleagues want to play a trick on you—but it's for your own good.
Medical research
Jan 16, 2013 |
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New discovery in autism-related disorder reveals key mechanism in brain development and disease
A new finding in neuroscience for the first time points to a developmental mechanism linking the disease-causing mutation in an autism-related disorder, Timothy syndrome, and observed defects in brain wiring, according to ...
Neuroscience
Jan 14, 2013 |
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