Medical research

Study explores in vivo role of ubiquinone in mouse model

(HealthDay)—Ubiquinone (UQ) does not act as an antioxidant in vivo, and partial restoration of UQ levels and mitochondrial function can reverse severe disease phenotypes and shortened lifespan, according to an experimental ...

Genetics

Focusing in on high-resolution network biology

A central challenge in genetics is to understand how changes in DNA result in observable changes in an organism; how genotype maps to phenotype. As genes and their protein products do not act in isolation, connecting genotype ...

Pediatrics

Earlier adiposity rebound linked to metabolic syndrome

(HealthDay)—The age of adiposity rebound (AR), at which time body mass index (BMI) starts to rise after infancy, is associated with future development of metabolic syndrome, according to a study published online Dec. 23 ...

Oncology & Cancer

Implications of very low risk prostate cancer assessed

(HealthDay)—The risk of adverse findings at surgery for men with very low risk (VLR) prostate cancer is significantly lower than for those with low risk (LR), according to research published in the October issue of the ...

Diabetes

Genetic link to gestational diabetes

New Northwestern Medicine research on the genetics of diabetes could one day help women know their risk for developing gestational diabetes before they become pregnant—and lead to preventive measures to protect the health ...

Oncology & Cancer

Researchers offer new insights on cancer cell signaling

(Medical Xpress)—A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process that is activated across a vast ...

Genetics

Candidate drug provides benefit in SMA animal models

In a new publication that appears in Human Molecular Genetics, the laboratory of Christine DiDonato, PhD reports on their pharmacological characterization of the drug RG3039, demonstrating that it can extend survival and ...

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