(Medical Xpress)—One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body. In order to investigate ...
Oct 18, 2013
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The Allen Institute for Brain Science announced today the discovery of a new class of cells in the spinal cord that act like neural stem cells, offering a fresh avenue in the search for therapies to treat spinal cord injury ...
Sep 15, 2011
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The DiMelli (Diabetes Mellitus Incidence Cohort Registry) study examines the frequency and characteristics of diabetes phenotypes in children and young adults below the age of 20. The study was commissioned to investigate ...
Sep 12, 2013
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Cancer stem cells (CSCs), a key driver behind malignant cancer progression, are self-renewing, highly metastatic and therapeutically resistant. As cancer progresses, cancer cells display a phenotypic plasticity between the ...
Apr 1, 2022
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Three newly-defined phenotypes (observable characteristics or traits for an individual) that capture genetic associations which may provide protection against SARS-CoV-2, are presented in a study published in Nature Genetics. ...
Apr 12, 2022
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Laquinimod is an orally available synthetic compound that has been successfully evaluated in phase II/III clinical studies for the treatment of relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of laquinimod ...
Dec 6, 2011
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Evaluating the genetic correlations across our phenotypes is of essential importance for understanding disease etiology and other potential causality. A new method—published in the journal Nature Genetics—vastly improves ...
Jul 2, 2020
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Leuven researchers led by professor Bart De Strooper (VIB-KU Leuven) have identified a new role for PARL, a protein linked to Parkinson's disease. In this week's edition of the Proceedings of the National Academy of Science, ...
Jan 3, 2019
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It is now widely understood that cancer is a disease of acquired defects in genes and gene function. An article published Feb. 9 in Science, and authored by Andrew Feinberg, M.D., of the Johns Hopkins Kimmel Cancer Center ...
Feb 10, 2023
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Copper is essential for many cellular functions, including cellular respiration, antioxidant defense, neurotransmitter biosynthesis and neuropeptide amidation, among others. Until recently, only two inborn errors of copper ...
Aug 18, 2022
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