News tagged with phosphorylation
Vitamin D linked to mitochondrial oxidative function
(HealthDay)—For vitamin D deficient individuals, cholecalciferol therapy is associated with reduced phosphocreatine recovery half-time in skeletal muscle and with improvements in fatigue, according to a ...
Health
Mar 19, 2013 |
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BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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Research team explains important step in the activation of T-cells in the immune system
A team, headed by Prof. Dr. Wolfgang Schamel from the Institute of Biology III of the University of Freiburg and Prof. Dr. Balbino Alarcón from the Center for Molecular Biology Severo Ochoa of the Autonomous ...
Immunology
Feb 07, 2013 |
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Enzyme CaM kinase II relaxes muscle cells: Researchers find overactive enzyme in failing hearts
A certain enzyme, the CaM kinase II, keeps the cardiac muscle flexible. By transferring phosphate groups to the giant protein titin, it relaxes the muscle cells. This is reported by researchers led by Prof. ...
Cardiology
Jan 17, 2013 |
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A protein's role in helping cells repair DNA damage
(Medical Xpress)—In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors.
Medical research
Nov 01, 2012 |
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Immune cells can be altered to help fight inflammatory diseases, research finds
(Medical Xpress)—A fundamental mechanism controlling cells of the human immune system could be key to helping fight inflammatory diseases such as rheumatoid arthritis and psoriasis, new research at the University of Dundee ...
Inflammatory disorders
Oct 11, 2012 |
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Mechanism of smoking-induced insulin resistance elucidated
(HealthDay)—Smoking-induced insulin resistance, which improves with smoking cessation, may be due to activation of mammalian target of rapamycin (mTOR), according to a study published online Sept. 10 in ...
Diabetes
Sep 17, 2012 |
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Study reveals new molecular target for melanoma treatment
A laboratory study led by UNC medical oncologist Stergios Moschos, MD, demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been ...
Cancer
Aug 17, 2012 |
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Giant raft of data to help us understand disease
Scientists at the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen have used a new method to assemble a massive catalogue of data on proteins. This gives them unprecedented insight into ...
Medical research
Jun 28, 2012 |
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Molecular 'on-off' switch for Parkinson's disease discovered
(Medical Xpress) -- Scientists at the Medical Research Council (MRC) Protein Phosphorylation Unit at the University of Dundee have discovered a new molecular switch that acts to protect the brain from developing Parkinson's ...
Parkinson's & Movement disorders
May 23, 2012 |
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Researchers identify drivers of sarcoma growth and survival
To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or ...
Cancer
May 02, 2012 |
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Neuroscientists discover key protein responsible for controlling nerve cell protection
A key protein, which may be activated to protect nerve cells from damage during heart failure or epileptic seizure, has been found to regulate the transfer of information between nerve cells in the brain. The discovery, made ...
Neuroscience
Apr 22, 2012 |
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Metal binding important for metformin action
(HealthDay) -- The ability of metformin to bind mitochondrial copper may be essential to its mechanism of action, according to a study published online April 9 in Diabetes.
Diabetes
Apr 14, 2012 |
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Signaling to chromatin
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH ...
Genetics
Jan 03, 2012 |
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Balancing the womb
(Medical Xpress) -- New research hopes to explain premature births and failed inductions of labour.
Medical research
Dec 21, 2011 |
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Phosphorylation
Phosphorylation is the addition of a phosphate (PO43-) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes.
Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2009, the Medline database returns nearly 160,000 articles on the subject, largely on protein phosphorylation).
For more information about Phosphorylation, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
