GZ17-6.02 with proteasome inhibitors kills multiple myeloma cells
A new research paper titled "GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells" has been published in Oncotarget.
Mar 6, 2024
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A new research paper titled "GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells" has been published in Oncotarget.
Mar 6, 2024
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When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...
Feb 28, 2024
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Heart failure stands as a leading cause of mortality worldwide, demanding advanced treatment options. Despite the urgency for more effective treatments, options for severe heart failure remain limited. Cell transplantation ...
Feb 21, 2024
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Researchers have discovered that a protein called phosphorylated α-synuclein, which is associated with several neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, is also involved in the normal ...
Jan 9, 2024
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A new research paper was published in Oncotarget is titled, "Osteopontin induces mitochondrial biogenesis in deadherent cancer cells."
Dec 4, 2023
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A new editorial paper was published in Oncotarget, titled "Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors."
Nov 8, 2023
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An experimental drug can reduce the toxic changes in tau proteins known to damage neurons in brains with Alzheimer's disease, researchers from Yale School of Medicine and Johns Hopkins University report.
Nov 6, 2023
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A new research paper titled "Metabolic switch in the aging astrocyte supported via integrative approach comprising network and transcriptome analyses" has been published in Aging.
Oct 24, 2023
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A team led by researchers at Purdue University and Purdue spinoff company Tymora Analytical Operations has developed a technique that may reveal signs of Parkinson's disease in urine samples.
May 16, 2023
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A new research paper was published in Oncotarget's, titled "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation."
Apr 26, 2023
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Phosphorylation is the addition of a phosphate (PO43-) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes.
Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2009, the Medline database returns nearly 160,000 articles on the subject, largely on protein phosphorylation).
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