Ophthalmology

MTHFR polymorphism, higher homocysteine up cataract risk

(HealthDay)—Methylenetetrahydrofolate reductase (MTHFR) polymorphism and elevated homocysteine levels contribute to the risk of cortical cataract, separately and together, according to a study published online March 17 ...

Medical research

PERK-opathies: Stress mechanism underlying neurodegeneration

A major challenge in the field of neurodegeneration is the unclear understanding of neuronal dysfunction. Elucidation of these patho-mechanisms could result in the identification of novel therapeutic targets. In this article, ...

Oncology & Cancer

CYP3A7*1C allele linked to cancer mortality, progression

(HealthDay)—The CYP3A7*1C allele appears to be associated with mortality and disease progression in specific cancers, according to a study published online March 10 in Cancer Research.

Diabetes

CYP2C19 polymorphisms impacts citalopram metabolism

(HealthDay)—For patients with major depressive disorder, certain CYP2C19 polymorphisms contribute to citalopram (CIT) metabolism, according to research published in the December issue of the Journal of Clinical Pharmacy ...

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