The first example of prion strains that replicate independently in vitro and in vivo suggests that strain diversity may be greater than previously thought, according to a study published October 18 in the open-access journal ...
Oct 18, 2018
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A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.
Sep 21, 2018
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A landmark study published in the journal Brain from the Mario Negri Institute for Pharmacological Research of Milan and the University of Glasgow provides first evidence that just a single traumatic brain injury can generate ...
Aug 1, 2018
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A hamster prion that replicated under conditions of low RNA levels in mouse brain material resulted in altered disease features when readapted and transmitted back to hamsters, according to new research presented in PLOS ...
Jun 21, 2018
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Case Western Reserve University School of Medicine researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment ...
Jun 5, 2018
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Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have found little evidence ...
May 17, 2018
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Chronic wasting disease (CWD) did not cross the species barrier to infect cynomolgus macaque monkeys during a lengthy investigation by National Institutes of Health scientists exploring risks to humans.
Apr 25, 2018
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Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations. To determine whether three of the unstudied mutations are transmissible, scientists from the National Institute ...
Mar 8, 2018
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National Institutes of Health scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the assay to offer the possibility of improving early diagnosis of Parkinson's disease and ...
Feb 9, 2018
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An international team of researchers has found different disease type associations with distinct amyloid-beta prion strains in the brains of dead Alzheimer's patients. In their paper published in Proceedings of the National ...
