Team finds mechanism linking key inflammatory marker to cancer
In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.
Cancer
May 20, 2013 |
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Serotonin mediates exercise-induced generation of new neurons
Mice that exercise in running wheels exhibit increased neurogenesis in the brain. Crucial to this process is serotonin signaling. These are the findings of a study by researchers at the Max Delbrück Center ...
Neuroscience
May 13, 2013 |
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Scientists find potential therapeutic target for Cushing's disease
Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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Researchers discover link between inherited endocrine tumor syndrome and well-studied cell pathway
(Medical Xpress)—A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of ...
Cancer
Apr 24, 2013 |
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Tart cherries linked to reduced risk of stroke
(Medical Xpress)—For the millions of Americans at risk for heart disease or diabetes, a diet that includes tart cherries might actually be better than what the doctor ordered, according to new animal research ...
Health
Apr 24, 2013 |
3.8 / 5 (4) |
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Cancer cell metabolism kills
Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...
Cancer
Apr 15, 2013 |
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Naturally occurring substance proves effective against deadly skin cancer in laboratory tests
For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin ...
Cancer
Apr 10, 2013 |
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Preclinical study indicates potential for novel inhibitor to overcome drug resistance induced by RAF, MEK inhibitors
A new class of investigational medicines may help to treat patients with cancers driven by mutations in genes such as BRAF or KRAS/NRAS, including those patients who have become resistant to therapies that target BRAF directly, ...
Cancer
Apr 08, 2013 |
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Research suggests popular diabetes drugs can cause abnormal pancreatic growth in humans
(Medical Xpress)—Individuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine ...
Diabetes
Mar 27, 2013 |
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Researcher examines mechanism underlying abdominal pain in pancreatic cancer
Erxi Wu, assistant professor of pharmaceutical sciences, co-wrote the article, "Neurotransmitter substance P mediates pancreatic cancer perineural invasion via NK-1R in cancer cells," which was published by Molecular Cancer Re ...
Cancer
Mar 01, 2013 |
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Team finds general mechanism that accelerates tumor development
ICREA professor Raúl Méndez publishes a study in Nature describing how the CPBE1 protein "takes the brakes off" the production of proteins associated with the cell switch from being healthy to tumorous. ...
Cancer
Feb 24, 2013 |
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Scientists identify molecular system that could help develop potential treatments for neurodegenerative diseases
Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases.
Neuroscience
Feb 21, 2013 |
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Researchers say silencing of retinoblastoma gene regulates differentiation of myeloid cells
Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This mechanism includes silencing ...
Immunology
Feb 19, 2013 |
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Cervical cancer: First 3-D image of an HPV oncoprotein
(Medical Xpress)—For the first time, researchers from the Laboratoire biotechnologie et signalisation cellulaire at the Strasbourg-based Ecole supérieure de biotechnologie (CNRS/Université de Strasbourg) and Institut ...
Cancer
Feb 15, 2013 |
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Researchers find potential new therapeutic target for treating non-small cell lung cancer
Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune ...
Cancer
Feb 15, 2013 |
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