One step closer to understanding biology behind genetic variants linked to blood cell traits
(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute and University of Cambridge have unpicked genetic variants that affect the formation of blood cells. They found that around a third of ...
Genetics
Apr 17, 2013 |
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Recipe for large numbers of stem cells requires only one ingredient
Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...
Medical research
Apr 17, 2013 |
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Multicenter study confirms low testosterone in 84 percent of lung cancer patients taking crizotinib
A previous study by the University of Colorado Cancer Center reported the common side effect of low testosterone in men treated with the recently approved lung cancer agent, crizotinib. A new study published this week in ...
Cancer
Apr 16, 2013 |
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Transcription factors regulating blood oxygen linked to melanoma metastases
Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.
Cancer
Apr 16, 2013 |
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Study uncovers key factor in Alzheimer's progression
(Medical Xpress)—A new study from researchers at the University of Florida may have uncovered a critical factor that drives the relentless progression of Alzheimer's disease ― a discovery that could eventually slow its ...
Alzheimer's disease & dementia
Apr 16, 2013 |
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Cancer cell metabolism kills
Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...
Cancer
Apr 15, 2013 |
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Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
Platinum compounds, such as cisplatin and carboplatin, induce DNA cross-linking, prohibiting DNA synthesis and repair in rapidly dividing cells. They are first line therapeutics in the treatment of many solid tumors, but ...
Cancer
Apr 15, 2013 |
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Researchers untangle molecular pathology of giant axonal neuropathy
Giant axonal neuropathy (GAN) is a rare genetic disorder that causes central and peripheral nervous system dysfunction. GAN is known to be caused by mutations in the gigaxonin gene and is characterized by tangling and aggregation ...
Neuroscience
Apr 15, 2013 |
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Laser liposuction melts fat, results in tighter skin
A new, minimally invasive treatment that uses lasers to melt fat could replace the "tummy tuck," suggests research on more than 2,000 people being presented at the Society of Interventional Radiology's 38th Annual Scientific ...
Other
Apr 15, 2013 |
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Peptides for the treatment of severe diseases
A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively ...
Medical research
Apr 15, 2013 |
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Deciphering the cellular reading system of DNA methylation
(Medical Xpress)—Scientists from the FMI identify how a family of proteins reads the methylation marks on the DNA so critical for cell development. These MBD proteins bind directly to methylation marks ...
Genetics
Apr 12, 2013 |
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High-dose opioids disturb hormones long-term, but mental and physiologic function improves
Half of patients on high-dose, long-term opioid therapy had hormonal disturbances or signs of inflammation, while 100 percent reported improved pain control and mental outlook, new research shows. The results, reported today ...
Medications
Apr 11, 2013 |
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A novel surface marker helps scientists 'fish out' mammary gland stem cells
Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this ...
Cancer
Apr 11, 2013 |
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How Alzheimer's could occur: Protein spheres in the nucleus give wrong signal for cell division
A new hypothesis has been developed by researchers in Bochum on how Alzheimer's disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division. In the cell culture ...
Alzheimer's disease & dementia
Apr 11, 2013 |
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Fractalkine: New protein target for controlling diabetes
Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release ...
Diabetes
Apr 11, 2013 |
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