News tagged with pyruvate

Ability to chart the molecular progress of diabetes brings personalized medicine closer to realization

Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments ...

Diabetes Dec 19, 2012 | 5 / 5 (1) | 0

Team uses antisense technology that exploits gene splicing mechanism to kill cancer cells

Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. ...

Cancer Oct 31, 2012 | 5 / 5 (1) | 0 |

Metabolic protein wields phosphate group to activate cancer-promoting genes

A metabolic protein that nourishes cancer cells also activates tumor-promoting genes by loosening part of the packaging that entwines DNA to make up chromosomes, a team led by scientists at The University of Texas MD Anderson ...

Cancer Aug 16, 2012 | 3 / 5 (1) | 1

Study reveals details of alternative splicing circuitry that promotes cancer's Warburg effect

Cancer cells maintain their life-style of extremely rapid growth and proliferation thanks to an enzyme called PK-M2 (pyruvate kinase M2) that alters the cells' ability to metabolize glucose – a phenomenon known as the ...

Medical research Nov 02, 2011 | not rated yet | 0 |

Metabolic shift may offer early cancer clue

Cancer cells are well known for their altered metabolisms, which may help them generate the energy they need for rapid growth. Using an emerging imaging technology, researchers reporting in the July Cell Metabolism, a Cell ...

Cancer Jul 05, 2011 | not rated yet | 0 |