Whitehead Institute researchers have created a map of the DNA loops that comprise the three dimensional (3D) structure of the human genome and regulate gene expression in human embryonic stem (ES) cells and adult cells. The ...
Dec 10, 2015
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The olfactory sensory neurons in the nasal mucosa perceive the myriad smells in the air with the aid of odorant receptors. Each sensory neuron chooses one and only one receptor gene for expression. The probability that a ...
Nov 11, 2011
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Researchers at the Centre for Genomic Regulation (CRG) and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes. The findings, published in Nature Cell Biology, highlight ...
Oct 27, 2022
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Tumor suppressor genes protect cells from malignant transformation. If they are turned off as a result of chemical modifications in DNA, called epigenetic labels, this contributes to the development of cancer. As opposed ...
Jun 12, 2017
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In the largest study of its kind, genetic changes causing neurodevelopmental disorders have been discovered by scientists at the Wellcome Sanger Institute and their collaborators in the NHS Regional Genetics services. The ...
Mar 21, 2018
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Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study.
Jan 12, 2014
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There are roughly 20,000 genes and thousands of other regulatory "elements" stored within the three billion letters of the human genome. Genes encode information that is used to create proteins, while other genomic elements ...
Nov 10, 2014
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Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. Now, FMI researchers have identified a DNA region containing multiple regulatory elements that interact ...
Jun 6, 2023
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Researchers have developed a new strategy to improve the outcome of genome-wide association (GWA) studies.
Jun 30, 2011
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Since the sequencing of the human genome in 2001, all our genes – around 20,000 in total – have been identified. But much is still unknown – for instance where and when each is active. Next to each gene sits a short ...
Sep 10, 2012
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