News tagged with regulatory gene
Cells must use their brakes moderately for effective speed control
How cells regulate their own function by "accelerating and braking" is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. In a study published ...
Medical research
May 15, 2013 |
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Study uncovers molecular role of gene linked to blood vessel formation
University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.
Medical research
Apr 29, 2013 |
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One step closer to understanding biology behind genetic variants linked to blood cell traits
(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute and University of Cambridge have unpicked genetic variants that affect the formation of blood cells. They found that around a third of ...
Genetics
Apr 17, 2013 |
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Researchers say silencing of retinoblastoma gene regulates differentiation of myeloid cells
Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This mechanism includes silencing ...
Immunology
Feb 19, 2013 |
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Cancer suppressor gene links metabolism with cellular aging
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer
Jan 13, 2013 |
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Staking out unknown genomic territory
Scientists have long known that the human genome is incredibly complex. However, after almost 10 years of hard work, a team of more than 400 scientists at 32 research institutions worldwide has finally made ...
Genetics
Jan 04, 2013 |
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Search for epigenetic decoder leads scientists to Rett Syndrome
(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...
Medical research
Dec 21, 2012 |
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Researchers discover how the deadly malaria parasite evades the immune system, make progress toward developing a cure
(Medical Xpress)—More than a million people die each year of malaria caused by different strains of the Plasmodium parasite transmitted by the Anopheles mosquito. The medical world has yet to find an effective ...
Medical research
Dec 03, 2012 |
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Identification of mutations common to half of all liver cancers provides leads for new therapeutics
Liver cancer is the sixth most common cancer worldwide and the third leading cause of cancer-associated deaths. Yet even for such a frequent and deadly disease, the pathogenesis of this cancer remains obscure. ...
Cancer
Nov 16, 2012 |
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Scientists discover gene switch important in cancer
Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer. In a study, published ...
Cancer
Nov 01, 2012 |
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Putting a 'HEX' on muscle regeneration
A complex genetic regulatory network mediates the regeneration of adult skeletal muscles. In this issue of the Journal of Clinical Investigation, researchers at the State University of New York Downstate Medical Center in Bro ...
Medical research
Oct 01, 2012 |
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Uncovering the genome's regulatory code
Since the sequencing of the human genome in 2001, all our genes – around 20,000 in total – have been identified. But much is still unknown – for instance where and when each is active. Next to each ...
Genetics
Sep 10, 2012 |
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ENCODE project: Yale team finds order amidst the chaos within the human genome
The massive Encyclopedia of DNA Elements (ENCODE) unveiled Sept. 5 reveals a human genome vastly more rich and complex than envisioned even a decade ago. In a key supporting paper published in the journal Nature, the lab of ...
Genetics
Sep 05, 2012 |
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ENCODE project: Millions of DNA switches that power human genome's operating system discovered
The locations of millions of DNA 'switches' that dictate how, when, and where in the body different genes turn on and off have been identified by a research team led by the University of Washington in Seattle. Genes make ...
Genetics
Sep 05, 2012 |
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New regulatory mechanism discovered in cell system for eliminating unneeded proteins
A faulty gene linked to a rare blood vessel disorder has led investigators to discover a mechanism involved in determining the fate of possibly thousands of proteins working inside cells.
Medical research
Aug 10, 2012 |
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