Naked mole-rats (NMRs)—the longest living rodents—show remarkable resistance to aging and cancer. NMRs have long fascinated those involved in aging research and cancer research. Now, for the first time, researchers from ...
Feb 8, 2022
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Huntington's disease (HD) is a dominantly inherited neurodegenerative disease characterized by expansion of the number of trinucleotide CAG repeats in the first exon of the HTT gene encoding the protein huntingtin. While ...
Researchers at the Francis Crick Institute have pieced together genetic and molecular changes that lead to a rare progressive neurodegenerative condition called ataxia with oculomotor apraxia 2.
Jan 20, 2022
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Around half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in various states of decay like an old fashioned 'pull your own' junkyard where parts ...
The nuclear envelope (NE) is composed of the outer nuclear membrane (ONM) and the inner nuclear membrane (INM), which are separated by the perinuclear space and joined at nuclear pore complexes. INM proteins play crucial ...
Dec 8, 2021
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A new study led by University of California, Irvine researchers has confirmed a link between altered DNA repair and increased DNA damage associated with spinocerebellar ataxia type 7 (SCA7), a debilitating, sometimes deadly ...
Nov 30, 2021
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A study using mice by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA reveals that cardiac muscle cells play a pivotal role in determining how the heart heals following ...
Nov 23, 2021
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Researchers at Baylor College of Medicine have uncovered a more detailed picture of how the intestinal epithelium—the lining of the intestines—heals itself after infection with rotavirus. A meticulous single-cell analytical ...
Nov 3, 2021
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Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it. Cold Spring ...
Oct 27, 2021
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A pathway helping the breast cancer protein BRCA1 repair damaged DNA has been identified by University of Queensland researchers in a study that will inform future targeted therapies.
Oct 21, 2021
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