Aberrant splicing of messenger RNAs encoding surface antigen CD22 leads to downregulation of this protein in pediatric B-lymphoblastic leukemia (B-ALL), rendering malignant cells resistant to the effects of CD22-directed ...
Jan 4, 2022
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Recently, researchers led by Prof. Lin Wenchu from the High Magnetic Field Laboratory, Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences (CAS), in collaboration with Prof. Shan Ge and Associate Prof. ...
Aug 18, 2021
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What kills most people who die from cancer is not the initial tumor. It's the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to different organs.
May 18, 2021
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Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the ...
Jan 14, 2021
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Ph.D. student Esmee Koedoot studied the underlying processes responsible for metastases in a dangerous type of breast cancer. She hopes to find new possibilities to fight the disease. In December 2019 she obtained her doctorate ...
Jan 13, 2020
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A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer's disease. The study, led by researchers at Baylor College of Medicine and the ...
Oct 8, 2019
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In a large-scale analysis of RNA from postmortem human brain tissue, researchers at the Icahn School of Medicine at Mount Sinai and Columbia University have identified specific RNA splicing events associated with Alzheimer's ...
Oct 8, 2018
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No one knows how many times in a day, or even an hour, the trillions of cells in our body need to make proteins. But we do know that it's going on all the time, on a massive scale. We also know that every time this happens, ...
Aug 30, 2018
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When scientists at ETH Zurich analysed very large amounts of genetic cancer data, they found previously unresearched molecular changes. These could help in developing new personalised cancer treatments.
Aug 6, 2018
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It took eight long years of research, but now an international team led by neuroscientists at Université de Montréal has discovered a basic molecular mechanism that better helps understand how Lou Gehrig's disease, or amyotrophic ...
Mar 19, 2018
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