News tagged with somatic mutations

New cancer type with PIK3CA mutations

A newly defined type of colorectal and endometrial cancer involves at least two somatic mutations in the mismatch repair genes (MMR): MLH1, MSH2, MSH6, PMS2. This double somatic MMR cancer has no germline mutations in the ...

Aug 16, 2016
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Molecular clocks control mutation rate in human cells

Every cell in the human body contains a copy of the human genome. Through the course of a lifetime all cells are thought to acquire mutations in their genomes. Some of the mutational processes generating these mutations do ...

Nov 09, 2015
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