News tagged with stem cells

Related topics: cells , embryonic stem cells , bone marrow , pluripotent stem cells , cancer cells

Zebrafish help to unravel Alzheimer's disease

New fundamental knowledge about the regulation of stem cells in the nerve tissue of zebrafish embryos results in surprising insights into neurodegenerative disease processes in the human brain. A new study by scientists at ...

Aug 19, 2014
popularity 5 / 5 (3) | comments 0

An attractive solution for heart repair

Stem cell therapy is a promising option for repairing heart tissue damaged by heart attack. However, the main obstacle to cardiac stem cell therapy also happens to be pretty difficult to get around – and ...

Aug 15, 2014
popularity 4.9 / 5 (9) | comments 0

A new way to model cancer

Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic flaw—but ...

Aug 06, 2014
popularity 5 / 5 (5) | comments 1

Stem cell

Stem cells are cells found in most, if not all, multi-cellular organisms. They are characterized by the ability to renew themselves through mitotic cell division and differentiating into a diverse range of specialized cell types. Research in the stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s. The two broad types of mammalian stem cells are: embryonic stem cells that are isolated from the inner cell mass of blastocysts, and adult stem cells that are found in adult tissues. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin or intestinal tissues.

Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture. Highly plastic adult stem cells from a variety of sources, including umbilical cord blood and bone marrow, are routinely used in medical therapies. Embryonic cell lines and autologous embryonic stem cells generated through therapeutic cloning have also been proposed as promising candidates for future therapies.

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