Four stranded DNA structures—known as G-quadruplexes—have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the ...
Aug 3, 2020
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A large team of researchers affiliated with a very large number of medical institutions across the U.S. and also three from Finland, two from Mexico, and one from the U.K. has mapped structural variants in 17,795 sequenced ...
Like pirates on a treasure hunt, St. Jude Children's Research Hospital scientists have created the first 3-D map of a mouse genome and used it to discover scientific gold. The gold includes insight from machine learning into ...
Sep 4, 2019
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Inside cells DNA is tightly wrapped around proteins and packed in a complex, 3-D structure called chromatin. Chromatin not only protects genetic material from damage, but also organizes the entire genome by regulating the ...
Jan 29, 2019
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Studying the three-dimensional structure of DNA and its dynamics is revealing a lot of information about gene expression, expanding our knowledge of how cells, tissues and organs actually work in health and disease. Properly ...
Oct 31, 2018
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Hidden in the tangled, repetitious folds of DNA structures called centromeres, researchers from Harvard Medical School and the Broad Institute have discovered the hiding place of 20 million base pairs of genetic sequence, ...
Aug 8, 2013
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Scientists from Harvard Medical School and the CSIR-Centre for Cellular and Molecular Biology in Hyderabad, India, provide evidence that modern-day India is the result of recent population mixture among divergent demographic ...
Aug 8, 2013
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Researchers at Iowa State University have identified an RNA structure in humans that could lead to a new treatment for spinal muscular atrophy, the leading genetic cause of death in babies and young children.
Jul 19, 2013
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How do organisms evolve into individuals that are distinguished from others by their own personal brain structure and behavior? Scientists in Dresden, Berlin, Münster, and Saarbrücken have now taken a decisive step towards ...
May 9, 2013
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Equipped with the zebrafish genome, researchers have designed a method to assay the function of each and every gene and to explore the effects genetic variation has on zebrafish. So far the team has generated one or more ...
Apr 17, 2013
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