News tagged with therapeutic target

Related topics: cancer cells , protein , mouse model , cancer , breast cancer




Potential new therapeutic target for a subset of aggressive breast cancers

Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now discovered that they can prevent the formation of metastases by blocking the receptor protein Plexin B1.

Cancer created Mar 01, 2012 | popularity 5 / 5 (1) | comments 0

Unraveling why children with Down syndrome have increased leukemia risk

Children with Down syndrome (DS) have an increased risk of developing leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia (ALL). Through their studies in a mouse model of DS, a ...

Genetics created Feb 22, 2012 | popularity 5 / 5 (1) | comments 0

Blocking telomerase kills cancer cells but provokes resistance, progression

Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...

Cancer created Feb 21, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Cell signaling discovery provides new hope for blood disorders

Walter and Eliza Hall Institute scientists have revealed new details about how cell signalling is controlled in the immune system, identifying in the process potential new therapeutic targets for treating severe blood disorders.

Medical research created Feb 16, 2012 | popularity 5 / 5 (2) | comments 0

Role of known cancer gene in ovarian cancer investigated

The role of a known cancer-causing gene in the development of the most lethal type of ovarian cancer is being investigated by researchers from the Walter and Eliza Hall Institute after they were awarded a Cure Cancer Australia ...

Cancer created Feb 14, 2012 | popularity 5 / 5 (1) | comments 0

Therapy targets leukemia stem cells

New research takes aim at stubborn cancer stem cells that are thought to be responsible for treatment resistance and relapse. The study, published by Cell Press in the February 14 issue of the journal Cancer Cell, provid ...

Cancer created Feb 13, 2012 | popularity 4 / 5 (4) | comments 0

The leading cause of death for diabetics: Getting to the heart of problem

Millions of people suffer from type 2 diabetes. The leading cause of death in these patients is heart disease. Joseph Hill and colleagues, at the University of Texas Southwestern Medical Center, Dallas, have now identified, ...

Diseases, Conditions, Syndromes created Feb 13, 2012 | popularity 5 / 5 (1) | comments 0

Researchers increase understanding of gene's potentially protective role in Parkinson's

Treatments for Parkinson's disease, estimated to affect 1 million Americans, have yet to prove effective in slowing the progression of the debilitating disease.

Neuroscience created Feb 07, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

A thought-provoking new therapeutic target for brain cancer?

Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...

Cancer created Feb 01, 2012 | popularity not rated yet | comments 0

New therapeutic target to combat liver cancer discovered

Spanish researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the ...

Cancer created Jan 26, 2012 | popularity not rated yet | comments 0

Three is the magic number: A chain reaction required to prevent tumor formation

Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...

Cancer created Jan 20, 2012 | popularity 5 / 5 (1) | comments 0

Unexpected discovery opens up new opportunities for targeting cancer

Scientists at the University of Leicester have opened up a whole new approach to the therapeutic intervention for a family of anti-cancer drug targets, thanks to a completely new and unexpected finding.

Cancer created Jan 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers map potential genetic origins, pathways of lung cancer in nonsmokers

Researchers at the Translational Genomics Research Institute (TGen) have begun to identify mutations and cellular pathway changes that lead to lung cancer in never-smokers -- a first step in developing potential therapeutic ...

Cancer created Jan 09, 2012 | popularity 2 / 5 (1) | comments 0

New research finds trigger for breast cancer spread

Research led by Shyamal Desai, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has discovered a key change in the body's defense system that increases the potential ...

Cancer created Jan 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers find link between pulmonary inflammation, diesel exhaust, house dust

A study conducted by researchers at Boston University School of Medicine (BUSM) has found that diesel exhaust particulates (DEP) and house dust extract (HDE) causes pulmonary inflammation that aggravates asthma. The study ...

Health created Dec 14, 2011 | popularity 5 / 5 (1) | comments 0