Medical research

In cystic fibrosis, lungs feed deadly bacteria

In cystic fibrosis, Pseudomonas aeruginosa is a much-feared pathogen. The bacterium easily colonizes the lungs of people with cystic fibrosis, leading to chronic infections that are almost impossible to eradicate and are ...

Diseases, Conditions, Syndromes

Rare inherited enzyme disorder yields insight into fibrosis

What can a family of rare inherited disorders teach scientists about more common health problems like fibrosis? Plenty, based on research led by St. Jude Children's Research Hospital scientists that appears today in the journal ...

Medical research

Connective tissue on the wrong road—When organs start to scar

Scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Medicine 3—Rheumatology and Immunology, headed by Prof. Dr. Georg Schett, have now decrypted a molecular network that could in future ...

Diseases, Conditions, Syndromes

Infinite hug mechanism may be key to lung fibrosis

Researchers have long known that fibrosis – scarred tissue and organs – is caused by a wound healing mechanism that goes awry beyond normal wound repair. Now, a group of researchers at the University of Toronto's Faculty ...

Immunology

Life-threatening lung disease averted in experimental models

Idiopathic pulmonary fibrosis (IPF) is a fatal condition that leaves lung tissue permanently scarred and leads to the decline and eventual failure of the respiratory system. For those diagnosed with the disease, treatment ...

Diseases, Conditions, Syndromes

Metformin reverses established lung fibrosis

Researchers at the University of Alabama at Birmingham have shown—for the first time—that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

Diseases, Conditions, Syndromes

Lung-on-a-chip simulates pulmonary fibrosis

Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy.

Diseases, Conditions, Syndromes

Preventing fibrosis

Researchers at Cardiff University and the Wales Kidney Research Unit have discovered a potential new method for preventing the process that causes scar formation in organs.

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