A breakthrough has been made in the fight against Alzheimer's disease—researchers have found a new way to target the toxic particles that destroy healthy brain cells.
Sep 24, 2018
0
1053
The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...
Aug 24, 2018
0
104
Nearly a half-billion people worldwide live with type 2 diabetes. Yet despite the disease's sizeable and increasing impact, its precise causes remain murky. Current scientific thinking points to two key processes: insulin ...
Mar 9, 2018
0
129
In a new application of gene-editing technology, researchers at the Stanford University School of Medicine have gleaned insights into the genetic underpinnings of amyotrophic lateral sclerosis, a neurodegenerative disease ...
Mar 5, 2018
0
170
Alpha-synuclein, a sticky and sometimes toxic protein involved in Parkinson's disease (PD), blocks signals from an important brain growth factor, Emory researchers have discovered.
Sep 18, 2017
0
65
Group A Streptococcus bacteria—the cause of strep throat and flesh-eating infections—have been well studied for nearly a century. But researchers at University of California San Diego School of Medicine and Skaggs School ...
Aug 7, 2017
0
5
A toxic protein called amyloid beta is thought to play a key role in the onset of Alzheimer's disease. In healthy people, amyloid beta is degraded by enzymes as it forms. However, in patients with the disease, these enzymes ...
Mar 2, 2016
0
1387
A new test developed by UBC researchers allows physicians to measure the effects of gene silencing therapy in Huntington's disease and will support the first human clinical trial of a drug that targets the genetic cause of ...
Aug 7, 2015
0
215
Lysosomes, the "garbage disposal" systems of cells, are found in great abundance near the amyloid plaques in the brain that are a hallmark of Alzheimer's disease. Scientists have long assumed that their presence was helpful—that ...
Jun 30, 2015
1
177
A team of neuroscientists at Georgetown University Medical Center has shown how a protein, known to accumulate in Parkinson's disease and other neurodegenerative diseases, activates the brain's immune response.
May 12, 2015
0
109
