Researchers find possible 'master switch' in deadly brain cancer
(Medical Xpress)—Researchers at the University of Virginia School of Medicine have identified a promising target for treating glioblastoma, one that appears to avoid many of the obstacles that typically frustrate efforts ...
Cancer
May 23, 2013 |
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New study finds brain tumors can arise from neurons
(Medical Xpress)—Researchers from the US and Japan have shown that an aggressive type of brain tumor can arise from normal cells in the central nervous system such as neurons. The cells revert to an earlier, ...
Cancer
Oct 19, 2012 |
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Melanoma: Whole-genome sequencing of 25 tumors confirms role of sun damage, reveals new genetic alterations
Melanoma the deadliest and most aggressive form of skin cancer has long been linked to time spent in the sun. Now a team led by scientists from the Broad Institute and Dana-Farber Cancer Institute has sequenced ...
Cancer
May 09, 2012 |
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Experimental drug beneficial in NIH trial to treat a rare sarcoma
(Medical Xpress)—Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib. The results from ...
Cancer
May 07, 2013 |
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Newly identified tumor suppressor provides therapeutic target for prostate cancer
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain ...
Cancer
Apr 01, 2013 |
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Common antifungal drug decreases tumor growth and shows promise as cancer therapy
An inexpensive antifungal drug, thiabendazole, slows tumor growth and shows promise as a chemotherapy for cancer. Scientists in the College of Natural Sciences at The University of Texas at Austin made this ...
Cancer
Aug 21, 2012 |
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Analysis of mTOR shows how the protein works, how new generation of drugs may defeat it
Uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells, researchers at the University of California, San Francisco (UCSF) ...
Cancer
Feb 22, 2012 |
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Brain-building gene plays key role in gut repair
(Medical Xpress)—A gene with a colorful name – mindbomb 1 – plays a key role far beyond the brain. New research at Washington University School of Medicine in St. Louis shows that mindbomb 1 may be ...
Genetics
Apr 05, 2013 |
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Demystifying the immortality of cancer cells
(Medical Xpress) -- In cancer cells, normal mechanisms governing the cellular life cycle have gone haywire. Cancer cells continue to divide indefinitely, without ever dying off, thus creating rapidly growing ...
Cancer
Jul 05, 2012 |
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Gene deletion drives more than a quarter of breast cancers
A new study shows that the lack of a certain gene occurs in almost 28 percent of human breast cancers, playing a role in some 60,000 breast cancer cases in the United States and 383,000 worldwide this year.
Genetics
Aug 15, 2012 |
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Cancer may require simpler genetic mutations than previously thought
Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute ...
Cancer
May 25, 2012 |
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Genetic landscape of common brain tumors holds key to personalized treatment
Nearly the entire genetic landscape of the most common form of brain tumor can be explained by abnormalities in just five genes, an international team of researchers led by Yale School of Medicine scientists report online ...
Cancer
Jan 24, 2013 |
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Decoded: Molecular messages that tell prostate and breast cancers to spread
Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain ...
Cancer
Apr 30, 2013 |
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Scientists use luminescent mice to track cancer and aging in real-time
In a study published in the January 18 issue of Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth ...
Medical research
Jan 17, 2013 |
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Lack of protein Sp2 disrupts neuron creation in brain
(Medical Xpress)—A protein known as Sp2 is key to the proper creation of neurons from stem cells, according to researchers at North Carolina State University. Understanding how this protein works could ...
Neuroscience
Jan 14, 2013 |
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