News tagged with tumor growth

Poliovirus vaccine trial shows early promise for recurrent glioblastoma

An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.

Cancer created May 21, 2013 | popularity not rated yet | comments 0

Team finds mechanism linking key inflammatory marker to cancer

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

Cancer created May 20, 2013 | popularity not rated yet | comments 0 | with audio podcast

New protein-targeting drug shows promise in early trial for patients with high-risk CLL

A new oral targeted drug, idelalisib (GS-1101), has the potential to stave off the need for additional treatments for relapsed or treatment-resistant chronic lymphocytic leukemia (CLL), according to a study led in part by ...

Cancer created May 17, 2013 | popularity not rated yet | comments 0 | with audio podcast

Breakthrough in how pancreatic cancer cells ingest nutrients points to new drug target

In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a ...

Cancer created May 13, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Scientists define a new mechanism leading to tumor hypoxia

An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessel ...

Cancer created May 09, 2013 | popularity 5 / 5 (1) | comments 0

New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice

(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...

Cancer created May 08, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Experimental drug beneficial in NIH trial to treat a rare sarcoma

(Medical Xpress)—Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib. The results from ...

Cancer created May 07, 2013 | popularity not rated yet | comments 0

Exercise could reduce bone tumor growth

(Medical Xpress)—Weight-bearing exercise, often prescribed to combat bone loss, might have anti-cancer effects. Cornell biomedical researchers report that mechanical stimulation of cancerous bone, in making ...

Cancer created May 07, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists discover new target for personalized cancer therapy

A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...

Cancer created May 02, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study finds experimental drug inhibits growth in all stages of common kidney cancer

Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's ...

Cancer created Apr 30, 2013 | popularity not rated yet | comments 0

Protein improves efficacy of tumor-killing enzyme

Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio, the online open-access journal of the American Societ ...

Cancer created Apr 30, 2013 | popularity not rated yet | comments 0

VEGF may not be relevant biomarker for advanced prostate cancer

The well-studied protein VEGF does not appear to have any prognostic or predictive value for men with locally advanced prostate cancer, researchers from the Department of Radiation Oncology at Thomas Jefferson University ...

Cancer created Apr 29, 2013 | popularity not rated yet | comments 0

Clarifying the effect of stem cell therapy on cancer

Injection of human stem cells into mice with tumors slowed down tumor growth, finds research published in BioMed Central's open access journal Stem Cell Research & Therapy. Human mesenchymal stem cells (MSC), isolated from b ...

Cancer created Apr 29, 2013 | popularity not rated yet | comments 0

New study reveals how tumor suppressor p53 shut down in metastatic melanoma

Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way ...

Cancer created Apr 25, 2013 | popularity not rated yet | comments 0 | with audio podcast

Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

Cancer created Apr 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Transforming growth factor

Transforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.

The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.

For more information about Transforming growth factor, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.