News tagged with tumor metabolism
Metabolic protein launches sugar feast that nurtures brain tumors
Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which ...
Cancer
Nov 26, 2012 |
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Researchers identify novel metabolic programs driving aggressive brain tumors
Researchers at Moffitt Cancer Center have identified metabolic signatures that may pave the way for personalized therapy in glioma, a type of tumor that starts in the brain.
Cancer
Nov 09, 2012 |
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A novel oncogenic network specific to liver cancer initiation
Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, ...
Cancer
Oct 07, 2012 |
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PET predicts early response to treatment for head and neck cancer patients
Determining the optimal treatment course and predicting outcomes may get easier in the future for patients with head and neck sqaumous cell carcinomas (HNSCCs) with the use of an investigational imaging agent. Research published ...
Cancer
Oct 01, 2012 |
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Do you want to know another role of ribonucleotide reductase M2?
Ribonucleotide reductase (RR) is a target metabolic enzymes for cancer therapy. Few studies have described the correlation between RRM2 and the development of colorectal cancer. And the possible mechanism by which RRM2 mediates ...
Cancer
Sep 18, 2012 |
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Breast cancer risk linked to early-life diet and metabolic syndrome
Striking new evidence suggesting that diet and related factors early in life can boost the risk for breast cancer—totally independent of the body's production of the hormone estrogen—has been uncovered by a team of researchers ...
Cancer
Sep 17, 2012 |
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HIF gene mutation found in tumor cells offers new clues about cancer metabolism
For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified in cancer tumor cells.
Cancer
Sep 06, 2012 |
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New research uncovers diverse metabolic roles for PML tumor suppressor gene
Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, ...
Cancer
Aug 30, 2012 |
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Chemists determine one way tumors meet their growing need
Behaving something like ravenous monsters, tumors need plentiful supplies of cellular building blocks such as amino acids and nucleotides in order to keep growing at a rapid pace and survive under harsh conditions. ...
Cancer
Aug 23, 2012 |
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DNA deletions promote cancer, collateral damage makes it vulnerable
Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vul ...
Cancer
Aug 15, 2012 |
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New probe provides vital assist in brain cancer surgery
A new probe developed collaboratively at Norris Cotton Cancer Center and Dartmouth College's Thayer School of Engineering uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue ...
Cancer
Jul 24, 2012 |
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How aging normal cells fuel tumor growth and metastasis
It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive.
Cancer
Jun 14, 2012 |
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Key enzyme plays roles as both friend and foe to cancer
A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of ...
Medical research
Jun 14, 2012 |
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State-of-the-art scanning detects more cancer in bone
Research revealed at the Society of Nuclear Medicine's 2012 Annual Meeting describes new approaches to imaging for the detection of tumors in complex cases of bone cancer. Hybrid imaging technology combining computed tomography ...
Cancer
Jun 11, 2012 |
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Researchers identify promising biomarkers and new therapeutic targets for kidney cancer
Using blood, urine and tissue analysis of a unique mouse model, a team led by UC Davis researchers has identified several proteins as diagnostic biomarkers and potential therapeutic targets for kidney cancer. Subject to follow-up ...
Cancer
May 31, 2012 |
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