Cancer cells can disrupt a metabolic pathway that breaks down fats and proteins to boost the levels of a byproduct called methylmalonic acid, thereby driving metastasis, according to research led by scientists at Weill Cornell ...
Apr 13, 2022
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A new paper in Nature Communications reveals new insights into adaptations made by cancer cells to rewire their metabolism to achieve growth and survive. Among the discoveries include a challenge to a well-known feature in ...
Mar 23, 2022
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Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers ...
Mar 10, 2022
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Pancreatic cancer is a rare, yet elusive and deadly cancer, with a five-year survival rate of about 10%. If the cancer has metastasized, that rate lowers to 3%. And treatment options are extremely limited.
Jan 21, 2022
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A research team with the Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences reported their discovery that a metabolic regulation mechanism may play a role in malignant transformation of non-alcoholic ...
Nov 29, 2021
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Researchers have identified a metabolic enzyme and pathway in some triple-negative breast cancer (TNBC) patients, which they hope could serve as a biomarker to select patients to receive targeted therapy.
Nov 16, 2021
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According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks ...
Aug 25, 2021
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In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized "killer" T cells. Salk researchers led by Professor Susan Kaech have found that the environment inside tumors ...
Jun 10, 2021
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Today in Nature Communications, researchers at Huntsman Cancer Institute at the University of Utah report critical new insights into how cells mount an attack against melanoma tumors.
May 11, 2021
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Mount Sinai researchers uncovered a mechanism that tumor cells exploit selective autophagy for metabolic reprogramming that benefits tumor cell growth and offers resistance to glucose deprivation. The study suggests that ...
Apr 1, 2021
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