News tagged with tumor metabolism
Cancer cell metabolism kills
Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...
Cancer
Apr 15, 2013 |
5 / 5 (7) |
0
|
Researchers identify critical metabolic alterations in triple-negative breast cancer cells
Researchers at Fox Chase Cancer Center have identified a host of small molecules critical to metabolism in cells of triple-negative breast cancer—one of the least understood groups of breast cancer. These molecules, called ...
Cancer
Apr 09, 2013 |
not rated yet |
0
A fly mutation suggests a new route for tackling ALS
A team of researchers, led by Marc Freeman, PhD, an early career scientist with the Howard Hughes Medical Institute and associate professor of neurobiology at the University of Massachusetts Medical School have discovered ...
Genetics
Apr 08, 2013 |
4 / 5 (1) |
0
Mitochondrial metabolic regulator SIRT4 guards against DNA damage
(Medical Xpress)—Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.
Cancer
Apr 05, 2013 |
5 / 5 (4) |
2
|
The metabolic weathervane of cancer
Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from ...
Cancer
Apr 01, 2013 |
not rated yet |
0
|
Scientists find potential loophole in pancreatic cancer defenses
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...
Cancer
Mar 27, 2013 |
5 / 5 (4) |
0
|
BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
5 / 5 (3) |
0
|
Study shows key enzyme missing from aggressive form of breast cancer
A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain—providing insight ...
Cancer
Feb 28, 2013 |
5 / 5 (1) |
0
|
Scientists identify molecular link between metabolism and breast cancer
(Medical Xpress)—A protein associated with conditions of metabolic imbalance, such as diabetes and obesity, may play a role in the development of aggressive forms of breast cancer, according to new findings by researchers ...
Cancer
Feb 06, 2013 |
5 / 5 (1) |
0
|
How cancer cells rewire their metabolism to survive
Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar ...
Cancer
Jan 31, 2013 |
5 / 5 (4) |
0
Diabetes drug could hold promise for lung cancer patients
Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...
Cancer
Jan 29, 2013 |
not rated yet |
0
|
Study of cancer cell metabolism yields new insights on leukemia
University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have ...
Cancer
Jan 17, 2013 |
not rated yet |
0
Cancer suppressor gene links metabolism with cellular aging
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer
Jan 13, 2013 |
3.7 / 5 (3) |
0
|
Obesity and overeating during menopause together promote breast tumor growth and progression
Obese women might be able to eliminate their increased risk for postmenopausal breast cancer by taking measures during perimenopause to prevent weight gain and to therapeutically control the metabolic effects of their obesity, ...
Cancer
Dec 07, 2012 |
not rated yet |
0
Protein controlling glucose metabolism also a tumor suppressor
A protein known to regulate how cells process glucose also appears to be a tumor suppressor, adding to the potential that therapies directed at cellular metabolism may help suppress tumor growth. In their report in the Dec. ...
Cancer
Dec 06, 2012 |
5 / 5 (1) |
0
|
