Squamous cell carcinoma is a very unusual type of cancer. It occurs in many tissues—for example in the lungs, esophagus, pancreas, throat and pharynx, and on the skin. Due to the many mutations in this type of cancer, treatment ...
Mar 10, 2020
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The RAF protein could be a therapeutical target to treat tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine ...
Feb 20, 2020
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Researchers from VIB-UGent Center for Medical Biotechnology, University of Iowa (USA) and other collaborators, developed a novel approach to better understand a basic defense mechanism of our immune system. Central is ISG15, ...
Nov 26, 2019
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Traditional medicines mostly function as inhibitors, attacking the disease-relevant proteins that cause cancer, by binding to their accessible pockets. Following this strategy, only ~20% of all proteins are chemically addressable, ...
Aug 23, 2019
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Researchers at Tokyo Metropolitan Institute of Medical Sciences are reporting new insight into how the Parkinson's disease-associated protein Parkin selects its targets. Cells depend on Parkin to help get rid of damaged mitochondria. ...
May 20, 2019
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Lung adenocarcinoma is the most common type of lung cancer. Although various targeted drugs have been developed to treat it, they do not markedly improve the survival of patients. Part of the explanation for this impasse ...
Mar 7, 2019
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Mutations in RAS proteins initiate many of the most aggressive tumors, and the search for pharmacological inhibitors of these proteins has become a priority in the battle against cancer. Michail Steklov, Francesca Baietti, ...
Nov 16, 2018
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New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires' disease, findings that could have broad implications for development of medicines to fight ...
Nov 14, 2018
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The cerebral cortex is responsible for a large number of complex brain functions, ranging from the perception of sensory stimuli through alertness, memory and language to consciousness. Neurobiologists at the Max Planck Institute ...
Nov 5, 2018
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Could microbes in our guts be sending out the wrong message? Queen's University Belfast researchers have, for the first time, found a specific microbe in the gut that pumps out protein molecules that mimic a human protein, ...
Oct 29, 2018
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