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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
Global telemedicine therapy for dementia shows benefit in clinical trial
For people living with primary progressive aphasia (PPA), a rare, early-onset neurodegenerative dementia that predominantly affects language abilities, something as simple as ordering their favorite meal at a drive-thru can ...
Apr 18, 2025
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Alzheimer's disease & dementia
Modulating the brain's immune system may curb damage in Alzheimer's
New research suggests that calming the brain's immune cells might prevent or lessen the damaging inflammation seen in Alzheimer's disease. The study points to the key role of the hormone and neurotransmitter norepinephrine, ...
Apr 17, 2025
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Gene 'reversal' in fruit flies points to new hope for Alzheimer's treatment
A study published in The American Journal of Human Genetics by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital provides solutions ...
Apr 17, 2025
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Mouse model reveals how the Icelandic mutation protects against Alzheimer's disease
RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in animals for the first time. This could eventually lead to the development of new ways to treat the neurodegenerative ...
Apr 17, 2025
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Five reasons why young-onset dementia is often missed
Around 57 million people worldwide have dementia. While most cases of dementia are diagnosed in older adults, about 7% of cases occur in people under 65. This number may be even higher as young-onset dementia continues to ...
Apr 17, 2025
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Hereditary Alzheimer's: Blood marker for defective neuronal connections rises early
Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms. This is evident in the levels ...
Apr 16, 2025
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EU approves sale of new Alzheimer's drug, with conditions
The European Commission said Wednesday that it had given formal approval for Leqembi, a long-awaited new treatment for early-stage Alzheimer's disease, to be sold in the EU under strict conditions.
Apr 16, 2025
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How do age, sex, hormones and genetics affect dementia biomarkers in the blood?
A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood. The study was published online in Neurology.
Apr 16, 2025
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Menopause at an early age can exacerbate cognitive decline
A team of researchers from the Tohoku University Graduate School of Medicine and Tokyo Metropolitan Institute of Medical Science found that women who entered menopause before the age of 40 had worse cognitive outcomes than ...
Apr 16, 2025
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Repetitive transcranial magnetic stimulation shows promise in Alzheimer's treatment
Santa Lucia Foundation IRCCS-led research is reporting that repetitive transcranial magnetic stimulation (rTMS) targeting the precuneus may slow the progression of cognitive decline, impairments in daily functioning, and ...
AI tool unlocks longstanding misfolding mystery behind Alzheimer's and Parkinson's diseases
A novel artificial intelligence (AI) tool has revealed how disease-linked proteins misfold into harmful structures, a key advance in understanding neurodegenerative disorders such as Alzheimer's and Parkinson's.
Apr 15, 2025
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New study finds no evidence technology causes 'digital dementia' in older people
In the 21st century, digital technology has changed many aspects of our lives. Generative artificial intelligence (AI) is the latest newcomer, with chatbots and other AI tools changing how we learn and creating considerable ...
Apr 15, 2025
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As dementia rates increase, experts warn hospital emergency rooms are underprepared
At her mother's home in Illinois, Tracy Balhan flips through photos of her dad, Bill Speer. In one picture, he's smiling in front of a bucket of sweating beers and wearing a blue T-shirt that reads, "Pops. The man. The myth. ...
Apr 15, 2025
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Scientists identify key enzyme in Alzheimer's disease that links brain inflammation to memory loss
A research team at the Institute for Basic Science (IBS) has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD). The study, led by Director C Justin ...
Apr 14, 2025
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Hospital visits for cannabis use linked to higher dementia risk
Individuals with an emergency department (ED) visit or hospitalization due to cannabis were at 23% and 72% greater risk of a new dementia diagnosis within five years compared to individuals with an ED visit or hospitalization ...
Apr 14, 2025
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Technology use by older adults linked to reduced dementia risk
As the first generation that interacted with digital technology reaches an age where dementia risks emerge, scientists have asked the question: Is there a correlation between digital technology use and an increased risk of ...
Apr 14, 2025
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Being married linked to increased risk of dementia—new study
Would you believe me if I told you that staying single or ending your marriage could lower your odds of getting dementia? A new study led by researchers at Florida State University somewhat shockingly suggests that unmarried ...
Apr 14, 2025
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How savvy habits may help head off dementia
From slurping daily spoonfuls of fish oil to giving up alcohol, lifting weights and playing word games, older Americans think just about anything that might keep their brains sharp is worth a try.
Apr 14, 2025
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First participant with Down syndrome joins Alzheimer's prevention trial
Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor protein (APP) for the potential treatment of Alzheimer's disease (AD), which ...
Apr 11, 2025
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17 modifiable risk factors shared by stroke, dementia, and late-life depression
Seventeen modifiable risk factors are shared by stroke, dementia, and late-life depression, according to a review published online April 3 in the Journal of Neurology, Neurosurgery & Psychiatry.
Apr 10, 2025
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New reports suggest diabetes weight loss drugs could reduce Alzheimer's risk
Drugs originally developed to treat type 2 diabetes, particularly GLP-1 receptor agonists such as semaglutide (sold as Ozempic and Wegovy), are now drawing increased attention for their potential to protect brain health. ...
Having a father with Alzheimer's disease may be tied to a greater spread of tau protein in the brain
While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied to a greater spread of ...
Apr 9, 2025
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Human 'mini-brains' reveal protein GRAMD1B's potential role in neurodegeneration
Researchers at The Ohio State University Wexner Medical Center and College of Medicine have discovered a new way that neurons act in neurodegeneration by using human neural organoids—also known as "mini-brain" models—from ...
Apr 9, 2025
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More opportunities to test for Alzheimer's using new analytical method
A simpler method of analyzing blood samples for Alzheimer's disease has been tested in a large multicenter study led by Lund University in Sweden. "This is a major step in bringing simple blood tests for Alzheimer's disease ...
Apr 9, 2025
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Potential Alzheimer's disease therapeutic target identified in brain immune cells
Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer's disease (AD), but its role in the brain was unknown until now.
Apr 9, 2025
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