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Alzheimer's disease & dementia news
Diseases, Conditions, Syndromes
Alzheimer's changes appear early in patients with Down syndrome
Down syndrome is caused by an extra copy of chromosome 21. Because of genes present on this chromosome that are known to contribute to Alzheimer's disease, patients with Down syndrome often develop the disease, sometimes ...
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Neuroscience
Single enzyme failure found to drive neuron loss in dementia
Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis. The study provides ...
Dec 4, 2025
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Poor kidney health linked to higher levels of Alzheimer's biomarkers in blood
People with impaired kidney function have higher levels of Alzheimer's biomarkers in their blood, but not an increased risk of dementia, according to a study published in Neurology.
Dec 3, 2025
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Just 20 minutes of exercise twice a week may help slow dementia, study finds
How much physical activity—and how often—is needed to help stall dementia? For older adults with mild cognitive decline, there is now an answer: at least 20 minutes, at least twice weekly.
Dec 3, 2025
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How the brain protects itself from Alzheimer's disease
High levels of calcium are toxic to cells and contribute to loss of neurons in Alzheimer's disease. A new study published in JCI Insight identifies a mechanism through which the young brain protects itself against high calcium ...
Dec 3, 2025
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Breaking down barriers to accessing dementia-friendly eyecare
New accessible resources aim to make it easier for people with dementia and their families to access dementia-friendly eyecare.
Dec 3, 2025
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For those living with dementia, new study suggests shingles vaccine could slow the disease
An unusual public health policy in Wales may have produced the strongest evidence yet that a vaccine can reduce the risk of dementia. In a new study led by Stanford Medicine, researchers analyzing the health records of Welsh ...
Dec 2, 2025
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Impaired touch perception in Alzheimer's associated with Tau pathology and lower cognitive scores
Alzheimer's disease (AD) is a neurodegenerative condition characterized by the progressive deterioration of brain cells, which prompts memory loss, a decline in mental functions and behavioral changes. Estimates suggest that ...
Common health conditions can influence Alzheimer's blood tests
How do everyday health issues affect new blood tests for Alzheimer's disease? A study from Karolinska Institutet, published in Alzheimer's & Dementia, suggests that factors like kidney function, cholesterol, and diabetes ...
Dec 2, 2025
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Blood test shows obesity speeds Alzheimer's development
Researchers have conducted the first study evaluating the impact of obesity on Alzheimer's disease blood biomarkers (BBMs). BBM values increased up to 95% faster in individuals with obesity than in non-obese individuals, ...
Dec 2, 2025
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Switching risk and protective alleles improves Alzheimer's-disease-like signatures and disruptions in mice
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive degradation of brain cells, as well as an associated decline in memory and other mental functions. Earlier research found that different ...
Discovery about brain receptors may open the door to new Alzheimer's treatments
Researchers at Karolinska Institutet in Sweden and the RIKEN Center for Brain Science in Japan have identified two receptors in the brain that control the breakdown of amyloid beta, a substance that accumulates in Alzheimer's ...
Nov 29, 2025
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New AI technology can provide rapid and reliable dementia diagnosis
Researchers at Örebro University have developed two new AI models that can analyze the brain's electrical activity and accurately distinguish between healthy individuals and patients with dementia, including Alzheimer's ...
Nov 28, 2025
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An fMRI marker of Alzheimer's-related cognitive decline
Researchers at Université Savoie Mont Blanc, Radboud University and the University of Oxford's Wellcome Center for Integrative Neuroimaging, report that attenuation of the brain's intrinsic anticorrelation between the default ...
How antibody therapy clears Alzheimer's plaques: Key immune mechanism identified
Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline. Researchers from VIB and KU Leuven have now demonstrated the ...
Nov 25, 2025
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Key marker linking coronary artery disease to cognitive decline identified
Individuals with coronary artery disease (CAD)—a constricting or blocking of blood vessels feeding the heart—face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive ...
Nov 25, 2025
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Immediate treatment for traumatic brain injuries linked to lower risk for Alzheimer's disease
Getting treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease by up to 41%, according to new research from Case Western Reserve University.
Nov 25, 2025
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Novel discovery reveals how brain protein OTULIN controls tau expression and could transform Alzheimer's treatment
Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease. The findings, published in Genomic Psychiatry, ...
Nov 25, 2025
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Pill form of semaglutide fails to slow Alzheimer's in large trial
A pill version of semaglutide, the ingredient in Ozempic and Wegovy, did not slow the progress of Alzheimer's disease, drugmaker Novo Nordisk announced on Nov. 24.
Nov 25, 2025
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Hospital infections associated with higher risk of dementia
A large-scale meta-analysis, led by first author Wei Yu Chua from the National University of Singapore and corresponding author Eng-King Tan at the National Neuroscience Institute and Duke-NUS Medical School in Singapore, ...
Nov 25, 2025
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Rare mutation protects brain's immune cells from Alzheimer's disease
Rutgers neuroscientist Peng Jiang and his neuroscience colleague Mengmeng Jin have made a discovery they say could reshape how scientists think about Alzheimer's treatment.
Nov 24, 2025
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Reduction of amyloid-β using red OLED restores memory in Alzheimer's model
A Korean research team has identified the most effective OLED color capable of enhancing cognitive function in Alzheimer's patients. The OLED platform developed for this study can precisely control color, brightness, flicker ...
Nov 24, 2025
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Astrocytes clear amyloid plaques and preserve cognitive function in Alzheimer's mouse models
Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer's disease and preserves cognitive function. The mechanism involves ...
Nov 21, 2025
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How the cheese-noodle principle could help counter Alzheimer's
Researchers at the Paul Scherrer Institute PSI have clarified how spermine—a small molecule that regulates many processes in the body's cells—can guard against diseases such as Alzheimer's and Parkinson's: It renders ...
Nov 21, 2025
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Targeting brain immune cells could restore Alzheimer's-related lipid imbalance, research shows
More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid‐beta (amyloid) plaques and tau protein tangles. These observations ...
Nov 21, 2025
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