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Alzheimer's disease & dementia news

Alzheimer's disease & dementia

Microglia's inflammatory shift: How IL-12 accelerates Alzheimer's damage

Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear away cellular debris—including the plaques typical of Alzheimer's disease. However, as our brains ...

Alzheimer's disease & dementia

How does education affect Alzheimer's and dementia risk? It's about more than degree attainment

Education has long been associated with reduced risk of Alzheimer's disease and related dementias, but a new study reveals that this protection extends far beyond diplomas and degrees. Co-led by researchers at The University ...

Alzheimer's disease & dementia

Lowering bioenergetic age may help fend off Alzheimer's

A person's "bioenergetic age"—or how youthfully their cells generate energy—might be a key indicator of whether they're at risk of developing Alzheimer's disease, new research from Weill Cornell Medicine shows.

Alzheimer's disease & dementia

Portable AI system helps detect cognitive impairment

Mild cognitive impairment (MCI) can be an early indicator of Alzheimer's disease or dementia, so identifying those with cognitive issues early could lead to interventions and better outcomes. But diagnosing MCI can be a long ...

Alzheimer's disease & dementia

Curing Alzheimer's disease: Magic bullet or magic shotgun blast?

Why are researchers still fumbling in the quest to cure what is arguably one of the most important diseases confronting humankind—Alzheimer's disease? Despite decades of research, there is still no curative treatment for ...

Alzheimer's disease & dementia

At-home brain speed tests bridge cognitive data gaps

Online tests of women's reaction times offer insights into cognitive function and could help fill data gaps on early cognitive problems, potentially shedding light on dementia development later in life, finds a new study ...

Alzheimer's disease & dementia

Understanding the impact of a dementia board game

Specialist dementia researchers from the University of Liverpool have seen positive initial findings when analyzing the outcomes of a board game that shines a light on dementia inequalities. Their paper, "Co-producing a boardgame ...

Neuroscience

Q&A: Researcher discusses tau and its role in Alzheimer's

The effects of Alzheimer's disease are devastating: not being able to recognize loved ones, losing precious memories, losing the ability to perform simple tasks, suffering through mood swings, and so on. Not only are memory ...

Alzheimer's disease & dementia

Flagging dementia patients for better hospital care

Cedars-Sinai investigators are using electronic health records to identify hospitalized patients likely to have dementia. The method they developed, detailed in a study published in the Journal of the American Geriatrics ...

Alzheimer's disease & dementia

'Exhausted' immune cells may drive Alzheimer's

Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable—eventually ...

Alzheimer's disease & dementia

Different biological variants discovered in Alzheimer's disease

Dutch scientists have discovered five biological variants of Alzheimer's disease, which may require different treatments. As a result, previously tested drugs may incorrectly appear to be ineffective or only minimally effective. ...

Health

High levels of HDL cholesterol tied to higher dementia risk

Elevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 in The Lancet Regional Health: Western Pacific.