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Arthritis & Rheumatism news
Oncology & Cancer
New approach to evaluating cases with rheumatic reactions to cancer immunotherapy
The prevalence and severity of rheumatic adverse reactions in cancer immunotherapy is significantly underestimated, due to the lack of standardized screening protocols for malignancies in patients with autoimmune disorders. ...
1 hour ago
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Arthritis & Rheumatism
Fine-tuning osteoclast development: A targeted approach to bone disease
Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often result from the dysregulation ...
5 hours ago
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Scientists uncover key clues to how a viral infection can lead to arthritis-like disease
Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world. The virus typically causes flu-like symptoms, but it can also trigger chronic, severe joint pain ...
May 20, 2025
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People with lupus who have certain antibodies are more likely to experience blood clots, researchers find
Some patients with lupus who possess specific antibodies are at a higher risk of thrombotic events such as a blood clot, stroke or heart attack, a new study led by Johns Hopkins Medicine researchers shows. The finding might ...
May 14, 2025
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Early structural changes in the knees common among people in their early 30s—often without symptoms
Mild structural changes visible in knee MRI scans are already common among adults in their thirties—even in those without knee pain or other symptoms. A study by the University of Oulu found signs of joint damage in more ...
May 5, 2025
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Assessing systemic sclerosis with AI deep neural networks
Artificial intelligence (AI) is shaping the future of health care, offering new tools for earlier diagnosis of disease and more precise tracking of treatment outcomes. In a new Yale-led study, published in Arthritis Research ...
May 5, 2025
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Explaining the link between 'good' gut bacteria and rheumatoid arthritis
After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, ...
May 2, 2025
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Tiny RNA molecule may hold the key to treating knee osteoarthritis
The number of people suffering from osteoarthritis is expected to top 1 billion by 2050. The biggest risk factor for the prevalent, often painful, chronic joint disease is aging. And like aging, there is currently no way ...
May 1, 2025
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JAK inhibitors show no increased cardiovascular risk in rheumatoid arthritis patients, large international study finds
An international research team led by Geneva University Hospital found no increase in cardiovascular events during the first two years of treatment with Janus kinase inhibitors (JAKi) compared to tumor necrosis factor inhibitors ...
Sema3A signaling molecule found to have significant cartilage-protective effects in osteoarthritis
Osteoarthritis (OA), a common degenerative joint disease that affects millions of people worldwide, particularly targets the knee joint. Over time, the cartilage within the joint wears down, leading to damage in the underlying ...
Apr 29, 2025
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Synovial fluid analysis provides accurate arthritis diagnosis in just 10 minutes
Dr. Ho Sang Jung and his research team from the Advanced Bio and Healthcare Materials Research Division at the Korea Institute of Materials Science (KIMS), in collaboration with Seoul St. Mary's Hospital, have developed a ...
Apr 28, 2025
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Repurposed diabetes drug can reduce pain for those with knee arthritis and overweight or obesity, clinical trial shows
A common diabetes drug can reduce the pain of people with knee osteoarthritis and overweight or obesity, possibly delaying the need for knee replacements, Monash University-led research has found.
Apr 25, 2025
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Specific patient characteristics might contribute to poor recovery after hip replacement surgery
Hip replacement surgery, or total hip arthroplasty (THA), can lessen pain and improve function in individuals with hip osteoarthritis, but some patients continue to experience long-term physical deficits—including muscle ...
Apr 23, 2025
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Emerging metabolic pathways in osteoarthritis: Insights from recent studies and therapeutic avenues
Osteoarthritis (OA) is one of the most prevalent conditions affecting tens of millions of U.S. adults, traditionally understood as a disease driven primarily by mechanical wear and tear. This perspective is being reshaped ...
Apr 16, 2025
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Immune cell 'messengers' could save crumbling bones—new hope for joint pain sufferers
A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse. Researchers have discovered that exosomes ...
Apr 14, 2025
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Blood biomarker could help identify patients at risk for severe scleroderma
Systemic sclerosis, or scleroderma, causes the hardening of skin and connective tissues. Often, the disease harms other organs, such as the heart, kidneys, lungs, and gastrointestinal tract, and it can lead to death.
Apr 14, 2025
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Yoga is as effective as strengthening exercises for knee osteoarthritis pain relief, study finds
Exercise therapy is suggested as a first-line treatment to improve joint pain and loss of function caused by osteoarthritis (OA), a musculoskeletal disorder that affects more than 595 million people worldwide. Yoga and strengthening ...
Biologic therapy significantly improves pregnancy outcomes in women with antiphospholipid syndrome
A clinical trial co-led by the Hospital for Special Surgery (HSS) has found that blocking inflammation with the drug certolizumab significantly reduces the risk of serious adverse pregnancy outcomes in women with antiphospholipid ...
Apr 11, 2025
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Massive genetic study uncovers potential osteoarthritis treatments
About one in five American adults have osteoarthritis, the most common form of arthritis, according to the Centers for Disease Control and Prevention. No treatment, however, exists to target the causes of the disease or to ...
Apr 9, 2025
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Study finds physicians treating chronic back pain need more education about axial spondyloarthritis
Many physicians who treat patients with chronic back pain lack the knowledge to identify people with axial spondyloarthritis, a chronic inflammatory disorder, and do not routinely screen for it, according to research led ...
Apr 3, 2025
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Scientists urge earlier diagnosis and treatment of psoriatic arthritis to prevent permanent damage
Delays in diagnosing and treating psoriatic arthritis—a common inflammatory disorder affecting around 200,000 people in the U.K.—are causing irreparable damage to people's health. This damage could be avoided by catching ...
Apr 1, 2025
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Flexible hydrogel could improve drug delivery for post-traumatic osteoarthritis treatment
Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms, but do not prevent or stop the progression of the condition. Although emerging therapies ...
Mar 31, 2025
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How might ACL surgery increase the risk of knee osteoarthritis?
Some individuals who have had anterior-cruciate-ligament reconstruction (ACLR), the kind of surgery often performed on athletes' knees, may develop early-onset knee osteoarthritis. A new study in the Journal of Orthopaedic ...
Mar 19, 2025
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New research leverages data science for disease prediction in the fight against rheumatoid arthritis
Fan Zhang, Ph.D., sees artificial intelligence as a pathway to finding an effective way to combat an intractable enemy: rheumatoid arthritis.
Mar 18, 2025
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Engineered stem cells automatically deliver arthritis drugs at prescribed times of day
With nearly 1.5 million people suffering from rheumatoid and juvenile arthritis in the United States, researchers at Shriners Children's St. Louis have discovered a revolutionary way to potentially minimize flare-ups and ...
Mar 6, 2025
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